The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 2 , Pages 377-386 , August 2010

Stereotactic body radiation therapy versus surgical resection for stage I non–small cell lung cancer

Presented in abstract form at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery, Boston, Massachusetts, May 9–13, 2009.

  • Traves D. Crabtree, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
    • Corresponding Author InformationAddress for reprints: Traves D. Crabtree, MD, 3108 Queeny Tower, One Barnes Jewish Hospital Plaza, St Louis, MO 63110.
  • ,
  • Chadrick E. Denlinger, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Bryan F. Meyers, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Issam El Naqa, PhD

      Affiliations

    • Department of Radiation Oncology, Washington University School of Medicine, St Louis, Mo
  • ,
  • Jennifer Zoole, BSN

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • A. Sasha Krupnick, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Daniel Kreisel, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • G. Alexander Patterson, MD

      Affiliations

    • Department of Thoracic Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Jeffrey D. Bradley, MD

      Affiliations

    • Department of Radiation Oncology, Washington University School of Medicine, St Louis, Mo

Received 10 May 2009 ,Revised 20 September 2009 ,Accepted 1 December 2009.

References 

  1. McGarry RC, Song G, des Rosieres P, Timmerman R. Observation-only management of early stage, medically inoperable lung cancer: poor outcome. Chest. 2002;121:1155–1158
  2. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM. Natural history of stage I non-small cell lung cancer: implications for early detection. Chest. 2007;132:193–199
  3. Baumann P, Nyman J, Hoyer M, Gagliardi G, Lax I, Wennberg B, et al. Stereotactic body radiotherapy for medically inoperable patients with stage I nonsmall cell lung cancer—a first report of toxicity related to COPD/CVD in a nonrandomized prospective phase II study. Radiother Oncol. 2008;88:359–367
  4. Lagerwaard FJ, Haasbeek CJ, Smit EF, Slotman BJ, Senan S. Outcomes of risk adapted fractionated stereotactic radiotherapy for stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2008;70:685–692
  5. Onishi H, Shirato H, Nagata Y, Hiraoka M, Fujino M, Gomi K, et al. Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non-small cell lung cancer: updated results of 257 patients in a Japanese multi-institutional study. J Thorac Oncol. 2007;2(7 Suppl. 3):S94–100
  6. Timmerman R, Papiez L, McGarry R, Likes L, DesRosiers C, Frost S, et al. Extracranial stereotactic radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer. Chest. 2003;124:1946–1955
  7. Onimaru R, Shirato H, Shimizu S, Kitamura K, Xu B, Fukumoto S, et al. Tolerance of organs at risk in small-volume, hypofractionated, image-guided radiotherapy for primary and metastatic lung cancers. Int J Radiat Oncol Biol Phys. 2003;56:126–135
  8. Uematsu M, Shioda A, Suda A, Fukui T, Ozeki Y, Hama Y, et al. Computed tomography–guided frameless stereotactic radiotherapy for stage I non-small cell lung cancer: a 5-year experience. Int J Radiat Oncol Biol Phys. 2001;51:666–670
  9. Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol. 2007;2:706–714
  10. Qiao X, Tullgren O, Lax I, Sirzen F, Lewensohn R. The role of radiotherapy in treatment of stage I non-small cell lung cancer. Lung Cancer. 2003;41:1–11
  11. Kang S, Luo R, Liao W, Wu H, Zhang X, Meng Y. Single group study to evaluate the feasibility and complications of radiofrequency ablation and usefulness of post treatment position emission tomography in lung tumours. World J Surg Oncol. 2004;2:30
  12. Pennathur A, Luketich JD, Abbas G, Chen M, Fernando HC, Gooding WE, et al. Radiofrequency ablation for the treatment of stage I non–small cell lung cancer in high-risk patients. J Thorac Cardiovasc Surg. 2007;134:857–864
  13. Sakurai J, Hiraki T, Mukai T, Mimura H, Yasui K, Gobara H, et al. Intractable pneumothorax due to bronchopleural fistula after radiofrequency ablation of lung tumors. J Vasc Interv Radiol. 2007;18:141–145
  14. Simon CJ, Dupuy DE. Current role of image-guided ablative therapies in lung cancer. Expert Rev Anticancer Ther. 2005;5:657–666
  15. Yamagami T, Kato T, Hirota T, Yoshimatsu R, Matsumoto T, Nishimura T. Pneumothorax as a complication of percutaneous radiofrequency ablation for lung neoplasms. J Vasc Interv Radiol. 2006;17:1625–1629
  16. Ginsberg RJ, Rubinstein LV. Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group. Ann Thorac Surg. 1995;60:615–622
  17. Kilic A, Schuchert MJ, Pettiford BL, Pennathur A, Landreneau JR, Landreneau JP, et al. Anatomic segmentectomy for stage I non-small cell lung cancer in the elderly. Ann Thorac Surg. 2009;87:1662–1666
  18. El-Sherif A, Gooding WE, Santos R, Pettiford B, Ferson PF, Fernando HC, et al. Outcomes of sublobar resection versus lobectomy for stage I non-small cell lung cancer: a 13-year analysis. Ann Thorac Surg. 2006;82:408–415
  19. Birdas TJ, Koehler RP, Colonias A, Trombetta M, Maley RH, Landreneau RJ, et al. Sublobar resection with brachytherapy versus lobectomy for stage Ib nonsmall cell lung cancer. Ann Thorac Surg. 2006;81:434–438
  20. Santos R, Colonias A, Parda D, Trombetta M, Maley RH, Macherey R, et al. Comparison between sublobar resection and 125Iodine brachytherapy after sublobar resection in high-risk patients with Stage I non-small-cell lung cancer. Surgery. 2003;134:691–697
  21. Hof H, Muenter M, Oetzel D, Hoess A, Debus J, Herfarth K. Stereotactic singledose radiotherapy (radiosurgery) of early stage nonsmall-cell lung cancer (NSCLC). Cancer. 2007;110:148–155
  22. Allen MS, Darling GE, Pechet TT, Mitchell JD, Herndon JE, Landreneau RJ, et al. Morbidity and mortality of major pulmonary resections in patients with earlystage lung cancer: initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg. 2006;81:1013–1019
  23. Harpole DH, DeCamp MM, Daley J, Hur K, Oprian CA, Henderson WG, et al. Prognostic models of thirty-day mortality and morbidity after major pulmonary resection. J Thorac Cardiovasc Surg. 1999;117:969–979
  24. Strand TE, Rostad H, Damhuis RA, Norstein J. Risk factors for 30-day mortality after resection of lung cancer and prediction of their magnitude. Thorax. 2007;62:991–997

 Disclosures: None.

PII: S0022-5223(10)00261-8

doi: 10.1016/j.jtcvs.2009.12.054

The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 2 , Pages 377-386 , August 2010