The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 2 , Pages 440-446, August 2010

Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury

  • Leo M. Gazoni, MD

      Affiliations

    • Department of Surgery, University of Virginia Health System, Charlottesville, Va
  • ,
  • Dustin M. Walters, MD

      Affiliations

    • Department of Surgery, University of Virginia Health System, Charlottesville, Va
  • ,
  • Eric B. Unger, BS

      Affiliations

    • Department of Surgery, University of Virginia Health System, Charlottesville, Va
  • ,
  • Joel Linden, PhD

      Affiliations

    • Department of Medicine, University of Virginia Health System, Charlottesville, Va
  • ,
  • Irving L. Kron, MD

      Affiliations

    • Department of Surgery, University of Virginia Health System, Charlottesville, Va
  • ,
  • Victor E. Laubach, PhD

      Affiliations

    • Department of Surgery, University of Virginia Health System, Charlottesville, Va
    • Corresponding Author InformationAddress for reprints: Victor E. Laubach, PhD, Department of Surgery, University of Virginia Health System, PO Box 801359, Charlottesville, VA 22908.

Received 20 August 2009; received in revised form 8 December 2009; accepted 1 March 2010. published online 16 April 2010.

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 This study was supported by National Institutes of Health R01HL092953 (to V.E.L. and I.L.K.), National Institutes of Health T32HL007849 (to I.L.K.), and the Roche Organ Transplant Research Foundation (to V.E.L.).

 Disclosures: Drs Linden and Kron were shareholders in Adenosine Therapeutics, LLC, the corporation that provided ATL-313, at the time of the study.

PII: S0022-5223(10)00232-1

doi:10.1016/j.jtcvs.2010.03.002

The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 2 , Pages 440-446, August 2010