The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1216-1223 , May 2010

Comparative glycomic profiling in esophageal adenocarcinoma

  • Zane T. Hammoud, MD

      Affiliations

    • Cardiothoracic Surgery, Henry Ford Health System, Detroit, Mich
    • Corresponding Author InformationAddress for reprints: Zane T. Hammoud, MD, Henry Ford Hospital, Cardiothoracic Surgery, K-14, 2799 W. Grand Blvd, Detroit, MI 48202.
  • ,
  • Yehia Mechref, PhD

      Affiliations

    • Indiana University, Bloomington, Ind
  • ,
  • Ahmed Hussein, PhD

      Affiliations

    • Indiana University, Bloomington, Ind
  • ,
  • Slavka Bekesova, PhD

      Affiliations

    • Indiana University, Bloomington, Ind
  • ,
  • Min Zhang, PhD

      Affiliations

    • Indiana University, Bloomington, Ind
  • ,
  • Kenneth A. Kesler, MD

      Affiliations

    • Indiana University School of Medicine, Indianapolis, Ind
  • ,
  • Milos V. Novotny, PhD

      Affiliations

    • Indiana University, Bloomington, Ind

Received 30 April 2009 ,Revised 26 September 2009 ,Accepted 11 December 2009.

References 

  1. Baldus SE, Wienand JR, Werner JP, Landsberg S, Drebber U, Hanisch FG, et al. Expression of MUC1, MUC2 and oligosaccharide epitopes in breast cancer: prognostic significance of a sialylated MUC1 epitope. Int J Oncol. 2005;27:1289–1297
  2. Dwek MV, Lacey HA, Leathem AJ. Breast cancer progression is associated with a reduction in the diversity of sialylated and neutral oligosaccharides. Clin Chim Acta. 1998;271:191–202
  3. Handerson T, Camp R, Harigopal M, Rimm D, Pawelek J. Beta 1,6-branched oligosaccharides are increased in lymph node metastases and predict poor outcome in breast carcinoma. J Clin Cancer Res. 2005;11:2969–2973
  4. Alper J. Glycobiology: turning sweet on cancer. Science. 2003;301:159–160
  5. Kyselova Z, Mechref Y, Kang P, Goetz JA, Dobrolecki LE, Sledge G, et al. Breast cancer diagnosis and prognosis through quantitative measurements of serum glycan profiles. Clin Chem. 2008;54:1166–1175
  6. An HJ, Miyamoto S, Lancaster KS, Kirmiz C, Li B, Lam KS, et al. Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer. J Proteome Res. 2006;5:1626–1635
  7. Kyselova Z, Mechref Y, Al Bataineh MM, Dobrolecki LE, Hickey RJ, Vinson J, et al. Alterations in serum glycome due to metastatic prostate cancer. J Proteome Res. 2007;6:1822–1832
  8. Goldman R, Ressom H, Varghese R, Goldman L, Bascug G, Loffredo C, et al. Detection of hepatocellular carcinoma using glycomic analysis. Clin Cancer Res. 2009;15:1808–1813
  9. Mechref Y, Novotny MV. Mass spectrometric mapping and sequencing of N-linked oligosaccharides derived from submicrogram amounts of glycoproteins. Anal Chem. 1998;70:455–463
  10. Kang P, Mechref Y, Klouckova I, Novotny MV. Solid-phase permethylation of glycans for mass spectrometric analysis. Rapid Commun Mass Spectrom. 2005;19:3421–3428
  11. Kang P, Mechref Y, Novotny MV. High-throughput solid-phase spin-column permethylation for MALDI-TOF-MS analysis. Rapid Commun Mass Spectrom. 2008;22:721–734
  12. Kruskal WH, Wallis WAJ. Errata to use of ranks in one-criterion variance analysis. J Am Stat Assoc. 1952;47:583–621
  13. Wilcoxon F. Individual comparisons by ranking methods. Biometrics. 1945;1:80–83
  14. Mas E, Pasqualini E, Caillol N, El Battari A, Crotte C, Lombardo D, et al. Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. Glycobiology. 1998;8:605–613
  15. Izawa M, Kumamoto K, Mitsuoka C, Kanamori C, Kanamori A, Ohmori K, et al. Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. Cancer Res. 2000;60:1410–1416
  16. Chandrasekaran EV, Xue J, Xia J, Chawda R, Piskorz C, Locke RD, et al. Analysis of the specificity of sialyltransferases toward mucin core 2, globo, and related structures. identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned α 2,3 (O) sialyltransferase. Biochemistry. 2005;44:15619–15635
  17. Peracaula R, Tabares G, Royle L, Harvey DJ, Dwek RA, Rudd PM, et al. Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins. Glycobiology. 2003;13:457–470
  18. Wada Y, Azadi P, Costello CE, Dell A, Dwek RA, Geyer H, et al. Comparison of the methods for profiling glycoprotein glycans—HUPO Human Disease Glycomics/Proteome Initiative Multi-Institutional Study. Glycobiology. 2007;17:411–422

 Disclosures: None.

PII: S0022-5223(10)00055-3

doi: 10.1016/j.jtcvs.2009.12.045

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1216-1223 , May 2010