The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages 1632-1636.e2 , June 2010

Infection after implantation of pulsatile mechanical circulatory support devices

  • William L. Holman, MD

      Affiliations

    • University of Alabama at Birmingham, Birmingham, Ala
    • Corresponding Author InformationAddress for reprints: William L. Holman, MD, Room 719 ZRB, 703 19th St S, Birmingham, AL 35294-0007.
    • ,
  • James K. Kirklin, MD

      Affiliations

    • University of Alabama at Birmingham, Birmingham, Ala
    • ,
  • David C. Naftel, PhD

      Affiliations

    • University of Alabama at Birmingham, Birmingham, Ala
    • ,
  • Robert L. Kormos, MD

      Affiliations

    • University of Pittsburgh, Pittsburgh, Pa
    • ,
  • Patricia Desvign-Nickens, PhD

      Affiliations

    • National Heart, Lung, and Blood Institute, Rockville, Md
    • ,
  • Margarita T. Camacho, MD

      Affiliations

    • Newark Beth Israel Medical Center, Newark, NJ
    • ,
  • Deborah D. Ascheim, MD

      Affiliations

    • Mount Sinai School of Medicine, New York, NY

Received 29 September 2009 ,Revised 16 December 2009 ,Accepted 2 January 2010.

References 

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  2. US Department of Health and Human Services. Artificial Heart and Assist Devices: Directions, needs, costs, societal and ethical issues. Bethesda: National Institutes of Health; 1985;
  3. el-Banayosy A, Arusoglu L, Kizner L, Tenderich G, Minami K, Inoue K, et al. Novacor left ventricular assist system versus HeartMate vented electric left ventricular assist system as a long-term mechanical circulatory support device in bridging patients: a prospective study. J Thorac Cardiovasc Surg. 2000 Mar;119:581–587
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  7. Deng MC, Loebe M, el-Banayosy A, Gronda E, Jansen PG, Vigano M, et al. Mechanical circulatory support for advanced heart failure: effect of patient selection on outcome. Circulation. 2001;103:231–237
  8. Frazier OH, Rose EA, Macmanus Q, Burton NA, Lefrak EA, Poirier VL, et al. Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. Ann Thorac Surg. 1992;53:1080–1090
  9. Goldstein DJ. Worldwide experience with the MicroMed DeBakey Ventricular Assist Device as a bridge to transplantation. Circulation. 2003;(Suppl):108;II272-7
  10. Portner PM, Jansen PG, Oyer PE, Wheeldon DR, Ramasamy N. Improved outcomes with an implantable left ventricular assist system: a multicenter study. Ann Thorac Surg. 2001;71:205–209
  11. Lietz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, et al. Outcomes of left ventricular assist device implantation as destination therapy in the post-REMATCH era: implications for patient selection. Circulation. 2007;116:497–505
  12. Long JW, Kfoury AG, Slaughter MS, Silver M, Milano CA, Rogers J, et al. Long-term destination therapy with the HeartMate XVE left ventricular assist device: improved outcomes since the REMATCH study. Congest Heart Fail. 2005;11:133–138
  13. Holman WL, Pamboukian SV, Bellot SC, Blood PS, Tallaj JA, Sharpton JL, et al. Use of an intraperitoneal ventricular assist device with a polytetrafluoroethylene barrier decreases infection. J Heart Lung Transplant. 2008;27:268–271
  14. Holman WL, Rayburn BK, McGiffin DC, Foley BA, Benza RL, Bourge RC, et al. Infection in ventricular assist devices: prevention and treatment. Ann Thorac Surg. 2003;75(suppl):S48–S57
  15. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky WP, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001;345:1435–1443
  16. Holman WL, Park SJ, Long JW, Weinberg A, Gupta L, Tierney AR, et al. Infection in permanent circulatory support: experience from the REMATCH Trial. J Heart Lung Transplant. 2003;23:1359–1365
  17. Holman WL, Kormos RL, Naftel DC, Miller MA, Pagani FD, Blume ED, et al. Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. J Heart Lung Transplant. 2009;28:44–50
  18. Pae WE, Connell JM, Adelowo A, Boehmer JP, Korfer R, el-Banayosy A, et al. Does total implantability reduce infection with the use of a left ventricular assist device? The LionHeart experience in Europe. J Heart Lung Transplant. 2007;26:219–229
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  21. Frazier OH, Gregoric ID, Cohn WE. Initial experience with non-thoracic, extraperitoneal, off-pump insertion of the Jarvik 2000 heart in patients with previous median sternotomy. J Heart Lung Transplant. 2006;25:499–503
  22. Westaby S, Katsumata T, Evans R, Pigott D, Taggart DP, Jarvik RK. The Jarvik 2000 Oxford system: increasing the scope of mechanical circulatory support. J Thorac Cardiovasc Surg. 1997;114:467–474

 Disclosures: Margarita T. Camacho reports fees and grant support from Thoratec.

PII: S0022-5223(10)00046-2

doi: 10.1016/j.jtcvs.2010.01.014

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages 1632-1636.e2 , June 2010

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