Left ventricular surgical restoration for anteroseptal scars: Volume versus shape

Calafiore, Antonio M.; Iacò, Angela L.; Amata, Davide; Castello, Cataldo; Varone, Egidio; Falconieri, Fabio; Bivona, Antonio; Gallina, Sabina; Di Mauro, Michele

doi:10.1016/j.jtcvs.2010.01.001

« Previous Next »The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1123-1130, May 2010

Left ventricular surgical restoration for anteroseptal scars: Volume versus shape

Read at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery, Boston, Mass, May 9–13, 2009.

Antonio M. Calafiore, MD
- Department of Adult Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia
- Address for reprints: Antonio M. Calafiore, MD, Department of Adult Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia.
Angela L. Iacò, MD
- Department of Adult Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia
Davide Amata, MD
- Department of Cardiac Surgery, University of Catania, Catania, Italy
Cataldo Castello, MD
- Department of Cardiac Surgery, University of Catania, Catania, Italy
Egidio Varone, MD
- Department of Cardiac Surgery, University of Catania, Catania, Italy
Fabio Falconieri, MD
- Department of Cardiac Surgery, University of Catania, Catania, Italy
Antonio Bivona, MD
- Department of Cardiac Surgery, University of Catania, Catania, Italy
Sabina Gallina, MD
- Institute of Cardiology, University of Chieti, Chieti, Italy
Michele Di Mauro, MD
- Department of Cardiac Surgery, Villa Bianca, Bari, Italy

Received 29 April 2009; received in revised form 26 November 2009; accepted 2 January 2010.

Objective

We report the long-term results of left ventricular surgical restoration in which 2 different strategies were used, which had restoration of ventricular volume or ventricular shape as their target.

Methods

From 1988 to 2008, 308 patients with anterior scars underwent elective left ventricular surgical restoration. Before 2002, a Dor procedure was performed in 107 cases to reduce left ventricular volume (group V); from 1998 to 2001, a Guilmet procedure was performed in 32 patients to rebuild a left ventricular conical shape (group S). From 2002, 169 patients (group S) underwent left ventricular surgical restoration to reshape a conical left ventricle by means of the Dor procedure (n = 29, septoapical scars) or septal reshaping (n = 140, when the septum was more involved than the anterior wall). The 2 groups were similar for all features but age, mitral regurgitation grade, mitral valve surgery rate (higher in group S), and ejection fraction (higher in group V).

Results

Early mortality was 7.8% (11.2% in group V vs 6.0% in group S, P = .102). Logistic regression showed that volume reduction was significantly related to higher early mortality. Five-year cardiac survival, cardiac event–free survival, and event-free survival were higher in group S. Cox analysis showed that the choice of volume reduction provided lower survival (hazard ratio, 2.1), cardiac survival (hazard ratio, 3.0), cardiac event–free survival (hazard ratio, 2.7), and event-free survival (hazard ratio, 2.2). When 30-day events were excluded, volume reduction was still a risk factor for cardiac event–free survival (hazard ratio, 2.2).

Conclusions

When the main target of left ventricular surgical restoration is left ventricular reshaping rather than left ventricular volume reduction, early and late outcomes seem to improve.

CTSNet classification: 17, 22, 23

Abbreviations and Acronyms: AMI, acute myocardial infarction, CABG, coronary artery bypass grafting, EF, ejection fraction, LV, left ventricular, LVSR, left ventricular surgical remodeling, MR, mitral regurgitation, NYHA, New York Heart Association, STICH, Surgical Treatment for Ischemic Heart Failure