The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 6 , Pages 1353-1360 , December 2010

The relationship of plasma transfusion from female and male donors with outcome after cardiac surgery

  • Ian J. Welsby, MBBS

      Affiliations

    • Department of Anesthesiology, Duke University Medical Center, Durham, NC
    • ,
  • Marla Troughton, MD

      Affiliations

    • Department of Pathology, University of Alabama, Birmingham, Ala
    • ,
  • Barbara Phillips-Bute, PhD

      Affiliations

    • Department of Anesthesiology, Duke University Medical Center, Durham, NC
    • ,
  • Rebecca Ramsey, MS

      Affiliations

    • Carolinas Region American Red Cross, Charlotte, NC
    • ,
  • Mary Lee Campbell, MT(ASCP)SBB

      Affiliations

    • Perioperative Services, Duke University Medical Center, Durham, NC
    • ,
  • Nicholas Bandarenko, MD

      Affiliations

    • Transfusion Medicine, Duke University Medical Center, Durham, NC
    • ,
  • Joseph P. Mathew, MD

      Affiliations

    • Department of Anesthesiology, Duke University Medical Center, Durham, NC
    • ,
  • Mark Stafford-Smith, MD

      Affiliations

    • Department of Anesthesiology, Duke University Medical Center, Durham, NC
    • Corresponding Author InformationAddress for reprints: Mark Stafford-Smith, MD, Department of Anesthesiology, Duke University Medical Center, Box 3094 DUMC, Durham, NC 27710.
    • ,
  • members of Cardiothoracic Anesthesiology Research Endeavors

      Affiliations

    • Cardiothoracic Anesthesiology Research Endeavors, Department of Anesthesiology, Duke University Medical Center, Durham, NC

Received 12 May 2009 ,Revised 16 September 2009 ,Accepted 20 December 2009.

References 

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  3. Strong M, Shoos-Lipton K. Transfusion-related acute lung injury. Association Bulletin #06-07 (November 3, 2006). Bethesda, MD: AABB; 2006;
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  16. Wright SE, Snowden CP, Athey SC, Leaver AA, Clarkson JM, Chapman CE, et al. Acute lung injury after ruptured abdominal aortic aneurysm repair: the effect of excluding donations from females from the production of fresh frozen plasma. Crit Care Med. 2008;36:1796–1802
  17. Gajic O, Yilmaz M, Iscimen R, Kor DJ, Winters JL, Moore SB, et al. Transfusion from male-only versus female donors in critically ill recipients of high plasma volume components. Crit Care Med. 2007;35:1645–1648
  18. Palfi M, Berg S, Ernerudh J, Berlin G, Palfi M, Berg S, et al. A randomized controlled trial of transfusion-related acute lung injury: is plasma from multiparous blood donors dangerous?. Transfusion. 2001;41:317–322
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  20. Silliman CC, Elzi DJ, Ambruso DR, Musters RJ, Hamiel C, Harbeck RJ, et al. Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium. J Leukoc Biol. 2003;73:511–524
  21. Khan SY, Kelher MR, Heal JM, Blumberg N, Boshkov LK, Phipps R, et al. Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury. Blood. 2006;108:2455–2462
  22. Eder AF, Herron R, Strupp A, Dy B, Notari EP, Chambers LA, et al. Transfusion-related acute lung injury surveillance (2003-2005) and the potential impact of the selective use of plasma from male donors in the American Red Cross. Transfusion. 2007;47:599–607
  23. Stainsby D, Jones H, Asher D, Atterbury C, Boncinelli A, Brant L, et al. Serious hazards of transfusion: a decade of hemovigilance in the UK. Transfus Med Rev. 2006;20:273–282
  24. Trotter A, Muck K, Grill HJ, Schirmer U, Hannekum A, Lang D. Gender-related plasma levels of progesterone, interleukin-8 and interleukin-10 during and after cardiopulmonary bypass in infants and children. Crit Care. 2001;5:343–348
  25. Seghaye MC, Qing M, von Bernuth G. Systemic inflammatory response to cardiac surgery: does female sex really protect?. Crit Care. 2001;5:280–282
  26. Kleinman S, Caulfield T, Chan P, Davenport R, McFarland J, McPhedran S, et al. Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel. Transfusion. 2004;44:1774–1789

 For members of Cardiothoracic Anesthesiology Research Endeavors, See Appendix 2.

 Disclosures: None.

PII: S0022-5223(09)01680-8

doi: 10.1016/j.jtcvs.2009.12.035

The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 6 , Pages 1353-1360 , December 2010

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