The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages e141-e142 , June 2010

Preserved homograft function 32 years after surgery in a young patient

  • Ismail El-Hamamsy, MD

      Affiliations

    • Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
  • ,
  • James T. Willerson, MD

      Affiliations

    • Department of Cardiology, Texas Heart Institute, Houston, Tex
  • ,
  • Magdi H. Yacoub, FRS

      Affiliations

    • Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    • Corresponding Author InformationAddress for reprints: Magdi H. Yacoub, FRS, Harefield Heart Science Center, Harefield Hospital, Hill End Rd, Harefield UB9 6JH, United Kingdom.

Received 12 August 2009 ,Accepted 9 December 2009.

References 

  1. Smith JD, Ogino H, Hunt D, Laylor RM, Rose ML, Yacoub MH. Humoral immune response to human aortic valve homografts. Ann Thorac Surg. 1995;60(2 Suppl):S127–S130
  2. Shetty R, Pibarot P, Audet A, Janvier R, Dagenais F, Perron J, et al. Lipid-mediated inflammation and degeneration of bioprosthetic heart valves. Eur J Clin Invest. 2009;39:471–480
  3. Lund O, Chandrasekaran V, Grocott-Mason R, Elwidaa H, Mazhar R, Khaghani A, et al. Primary aortic valve replacement with allografts over twenty-five years: valve-related and procedure-related determinants of outcome. J Thorac Cardiovasc Surg. 1999;117:77–90discussion 91
  4. Davies JE, Parker KH, Francis DP, Hughes AD, Mayet J. What is the role of the aorta in directing coronary blood flow?. Heart. 2008;94:1545–1547
  5. El-Hamamsy I, Zaki M, Stevens LM, Clark L, Rubens M, Melina G, et al. Rate of progression and functional significance of aortic valve and root calcification following freestyle versus homograft aortic root replacement: results from a prospective randomized trial. Circulation. In press.

 Disclosures: None.

PII: S0022-5223(09)01631-6

doi: 10.1016/j.jtcvs.2009.12.025

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages e141-e142 , June 2010