The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 4 , Pages 829-835.e13 , October 2010

Off-pump versus on-pump coronary artery bypass grafting: A systematic review and meta-analysis of propensity score analyses

  • Oliver Kuss, PhD

      Affiliations

    • Institute of Medical Epidemiology, Biostatistics, and Informatics, Faculty of Medicine, University of Halle-Wittenberg, Halle (Saale), Germany
    • Corresponding Author InformationAddress for reprints: Oliver Kuss, PhD, Institute of Medical Epidemiology, Biostatistics, and Informatics, Medical Faculty, University of Halle-Wittenberg, Magdeburger Str 8, 06097 Halle (Saale), Germany.
  • ,
  • Benita von Salviati, MS

      Affiliations

    • Institute of Medical Epidemiology, Biostatistics, and Informatics, Faculty of Medicine, University of Halle-Wittenberg, Halle (Saale), Germany
  • ,
  • Jochen Börgermann, MD

      Affiliations

    • Heart and Diabetes Center North Rhine-Westphalia, Department of Thoracic and Cardiovascular Surgery, Ruhr-University Bochum, Bad Oeynhausen, Germany

Received 28 April 2009 ,Revised 30 July 2009 ,Accepted 9 December 2009.

References 

  1. Mohr DN, Bauer J, Döbler K, Eckert O, Fischer B, Woldenga C. Qualität sichtbar machen. BQS Qualitätsreport 2005. Düsseldorf: BQS Bundesgeschäftsstelle Qualitätssicherung gGmbH; 2006;
  2. Sellke FW, DiMaio JM, Caplan LR, Ferguson TB, Gardner TJ, Hiratzka LF, et al. Comparing on-pump and off-pump coronary artery bypass grafting: numerous studies but few conclusions: a scientific statement from the American Heart Association council on cardiovascular surgery and anesthesia in collaboration with the interdisciplinary working group on quality of care and outcomes research. Circulation. 2005;111:2858–2864
  3. Sedrakyan A, Wu AW, Parashar A, Bass EB, Treasure T. Off-pump surgery is associated with reduced occurrence of stroke and other morbidity as compared with traditional coronary artery bypass grafting: a meta-analysis of systematically reviewed trials. Stroke. 2006;2759–2769
  4. Moller CH, Penninga L, Wetterslev J, Steinbruchel DA, Gluud C. Clinical outcomes in randomized trials of off- vs on-pump coronary artery bypass surgery: systematic review with meta-analyses and trial sequential analyses. Eur Heart J. 2008;29:2601–2616
  5. Wijeysundera DN, Beattie WS, Djaiani G, Rao V, Borger MA, Karkouti K, et al. Off-pump coronary artery surgery for reducing mortality and morbidity: metaanalysis of randomized and observational studies. J Am Coll Cardiol. 2005;46:872–882
  6. Rothwell PM. External validity of randomised controlled trials: “to whom do the results of this trial apply?”. Lancet. 2005;365:82–93
  7. Britton A, McKee M, Black N, McPherson K, Sanderson C, Bain C. Choosing between randomised and non-randomised studies: a systematic review. Health Technol Assess. 1998;2:i-124
  8. Straka Z, Widimsky P, Jirasek K, Stros P, Votava J, Vanek T, et al. Off-pump versus on-pump coronary surgery: final results from a prospective randomized study PRAGUE-4. Ann Thorac Surg. 2004;789–793
  9. Rosenbaum PR, Rubin DB. The central role of the propensity score in observational studies for causal effects. Biometrika. 1983;70:41–55
  10. Sturmer T, Joshi M, Glynn RJ, Avorn J, Rothman KJ, Schneeweiss S. A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol. 2006;59:437–447
  11. Cook EF, Goldman L. Performance of tests of significance based on stratification by a multivariate confounder score or by a propensity score. J Clin Epidemiol. 1989;42:317–324
  12. Cepeda MS, Boston R, Farrar JT, Strom BL. Comparison of logistic regression versus propensity score when the number of events is low and there are multiple confounders. Am J Epidemiol. 2003;158:280–287
  13. Rosenbaum PR, Rubin DB. Reducing bias in observational studies using subclassification on the propensity score. J Am Stat Assoc. 1984;79:516–524
  14. Rubin DB. Estimating causal effects from large data sets using propensity scores. Ann Intern Med. 1997;127:757–763
  15. Joffe MM, Rosenbaum PR. Invited commentary: propensity scores. Am J Epidemiol. 1999;150:327–333
  16. D'Agostino RB. Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med. 1998;17:2265–2281
  17. Blackstone EH. Comparing apples and oranges. J Thorac Cardiovasc Surg. 2002;123:8–15
  18. Kuper H, Nicholson A, Hemingway H. Searching for observational studies: what does citation tracking add to PubMed? A case study in depression and coronary heart disease. BMC Med Res Methodol. 2006;6:4
  19. Sweeting MJ, Sutton AJ, Lambert PC. What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data. Stat Med. 2004;23:1351–1375
  20. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F. Methods for metaanalysis in medical research. In:  Cressie NAC,  Fisher NI,  Johnstone IM,  Kadane JB,  Scott DW,  Silverman BW, et al. editor. Wiley series in probability and statistics. Chichester: Wiley; 2000;p. 1–317
  21. Zhang J, Yu KF. What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA. 1998;280:1690–1691
  22. Austin PC. Propensity-score matching in the cardiovascular surgery literature from 2004 to 2006: a systematic review and suggestions for improvement. J Thorac Cardiovasc Surg. 2007;134:1128–1135
  23. Takagi H, Tanabashi T, Kawai N, Kato T, Umemoto T. Off-pump coronary artery bypass sacrifices graft patency: meta-analysis of randomized trials. J Thorac Cardiovasc Surg. 2007;133:e2-e3
  24. Song HK, Petersen RJ, Sharoni E, Guyton RA, Puskas JD. Safe evolution towards routine off-pump coronary artery bypass: negotiating the learning curve. Eur J Cardiothorac Surg. 2003;24:947–952
  25. Sezai Y, Orime Y, Tsukamoto S. Coronary artery surgery results 2005 in Japan. Ann Thorac Cardiovasc Surg. 2007;13:220–223
  26. Novitzky D, Shroyer AL, Collins JF, McDonald GO, Lucke J, Hattler B, et al. A study design to assess the safety and efficacy of on-pump versus off-pump coronary bypass grafting: the ROOBY trial. Clin Trials. 2007;4:81–91

 Disclosures: Jochen Börgermann (as the principal investigator) and Oliver Kuss conducted a randomized trial to compare off-pump with on-pump coronary artery bypass grafting, which was sponsored in part by a grant from Medtronic, Düsseldorf, Germany. There was no external funding of the project reported, and all authors report no further conflicts of interest.

PII: S0022-5223(09)01625-0

doi: 10.1016/j.jtcvs.2009.12.022

The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 4 , Pages 829-835.e13 , October 2010