Repair of regurgitant bicuspid aortic valves: A systematic approach

Boodhwani, Munir; de Kerchove, Laurent; Glineur, David; Rubay, Jean; Vanoverschelde, Jean-Louis; Noirhomme, Philippe; El Khoury, Gebrine

doi:10.1016/j.jtcvs.2009.11.058

« Previous Next »The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 2 , Pages 276-284.e1, August 2010

Repair of regurgitant bicuspid aortic valves: A systematic approach

Presented at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery, May 9–13, 2009, Boston, Massachusetts.

Munir Boodhwani, MD, MMSc
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
- Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
- Address for reprints: Munir Boodhwani, MD, MMSc, Service de Chirurgie Cardiovasculaire et Thoracique, Cliniques Universitaires Saint-Luc UCL 90, Avenue Hippocrate 10, Brussels B-1200, Belgium.
Laurent de Kerchove, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
David Glineur, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
Jean Rubay, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
Jean-Louis Vanoverschelde, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
Philippe Noirhomme, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium
Gebrine El Khoury, MD
- Department of Cardiovascular and Thoracic Surgery Cliniques Universitaires Saint-Luc, Brussels, Belgium

Received 13 May 2009; received in revised form 5 September 2009; accepted 22 November 2009. published online 20 May 2010.

Objective

Patients with bicuspid aortic valves can present with aortic insufficiency caused by cusp disease or the aortic root pathology. We present our 13-year experience with a functional and systematic approach to bicuspid aortic valve repair.

Methods

Between 1995 and 2008, 122 consecutive patients (mean age, 44 ± 11 years) with bicuspid aortic valves underwent non-emergency valve repair for isolated aortic insufficiency (43%), aortic root dilatation (14%), or both (43%). Preoperative echocardiography identified aortic dilatation (n = 75), cusp prolapse (n = 96), and cusp restriction (n = 45) as mechanisms of aortic insufficiency. Raphé repair (n = 98) was performed by shaving (21%) or resection with primary closure (60%) or pericardial patch (18%). Functional aortic annuloplasty was performed using subcommissural annuloplasty (n = 51), ascending aortic replacement (n = 17), or aortic root replacement (n = 54) using a reimplantation (76%) or remodeling technique (24%).

Results

There was no operative mortality. Five patients underwent early aortic valve reoperation (3 re-repairs). At discharge, 93% of patients had aortic insufficiency grade 0/1 and 7% of patients had grade 2. Seven additional patients underwent aortic valve reoperation during follow-up (2 re-repairs). Overall survival was 97% ± 3% at 8 years. At 5 and 8 years follow-up, freedom from aortic valve reoperation was 94% ± 2% and 83% ± 5%, respectively, and freedom from aortic valve replacement was 96% ± 2% and 90% ± 5%, respectively. Freedom from recurrent aortic insufficiency (>2+) was 94% ± 3% at 5 years. Freedom from thromboembolism and bleeding was 96% ± 2% at 8 years.

Conclusion

A systematic approach to bicuspid aortic valve repair yields good early and midterm results. Repair of bicuspid valves for aortic insufficiency is a feasible and attractive alternative to mechanical valve replacement in young patients.

CTSNet classification: 35.1

Abbreviations and Acronyms: AI, aortic insufficiency, AV, aortic valve, BAV, bicuspid aortic valve