« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3
, Pages 591-599
, March 2010
Modulation of growth in human esophageal adenocarcinoma cells by group IIa secretory phospholipase A2
References
- . Marked regional variation in adenocarcinomas of the esophagus and the gastric cardia in the United States. Cancer. 2002;95:2096–2102
- . Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med. 1999;340:825–831
- . Multistage carcinogenesis in Barrett's esophagus. Cancer Lett. 2007;245:22–32
- . Inflammation promotes Barrett's metaplasia and cancer: a unique role for TNFα. Eur J Cancer Prev. 2001;10:163–166
- Involvement of oxidative stress in experimentally induced reflux esophagitis and Barrett's esophagus: clue for the chemoprevention of esophageal carcinoma by antioxidants. Mutat Res. 2001;480-481:189–200
- Secretory phospholipase A2 is required to produce histologic changes associated with gastroduodenal reflux in a murine model. J Thorac Cardiovasc Surg. 2008;135:1220–1227
- . The roles of sPLA2-IIA (Pla2g2a) in cancer of the small and large intestine. Front Biosci. 2008;13:4144–4174
- . Expression of inflammatory secretory phospholipase A2 and cytosolic phospholipase A2 in premalignant and malignant Barrett's oesophagus. Virchows Arch. 2004;444:426–435
- . A versatile tool for conditional gene expression and knockdown. Nat Methods. 2006;3:109–116
- . Phospholipase A2 as targets for anti-cancer drugs. Biochem Pharmacol. 2007;74:949–959
- . Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth. Mol Carcinog. 2007;46:106–116
- Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis. Nat Genet. 1997;17:88–91
- Expression of Pla2g2a prevents carcinogenesis in Muc2-deficient mice. Cancer Sci. 2008;99:2113–2119
- Inhibition of gastric cancer invasion and metastasis by PLA2G2A, a novel beta-catenin/TCF target gene. Cancer Res. 2008;68:4277–4286
- . Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and amplifies cytokine-mediated prostaglandin production in human rheumatoid synoviocytes. J Immunol. 2000;165:2790–2797
- . Cytosolic phospholipase A2 is required for cytokine-induced expression of type IIA secretory phospholipase A2 that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E2 generation in rat 3Y1 fibroblasts. J Biol Chem. 1998;273:1733–1740
- . The role of prostaglandins and other eicosanoids in the gastrointestinal tract. Gastroenterology. 2005;128:1445–1461
- . Prostaglandins and cancer. Gut. 2006;55:115–122
- Effects of selective PGE2 receptor antagonists in esophageal adenocarcinoma cells derived from Barrett's esophagus. Prostaglandins Other Lipid Mediat. 2006;81:150–161
- E series of prostaglandin receptor 2–mediated activation of extracellular signal–regulated kinase/activator protein-1 signaling is required for the mitogenic action of prostaglandin E2 in esophageal squamous-cell carcinoma. J Pharmacol Exp Ther. 2008;327:258–267
- Significance of COX-2 expression in human esophageal squamous cell carcinoma. Carcinogenesis. 2006;27:1214–1221
- Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res. 2004;10:6703–6709
- Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention. Carcinogenesis. 2005;26:785–791
- . Scalaradial inhibition of epidermal growth factor receptor-mediated Akt phosphorylation is independent of secretory phospholipase A2. J Pharmacol Exp Ther. 2005;314:1210–1217
- . Biphasic regulation of extracellular signal-regulated kinases by scalaradial, a secretory phospholipase A(2) inhibitor. Cancer Biol Ther. 2006;5:988–992
Disclosures: None.
Supported by University of Colorado Academic Enrichment Funds.
PII: S0022-5223(09)01563-3
doi: 10.1016/j.jtcvs.2009.10.061
© 2010 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3
, Pages 591-599
, March 2010
