The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 732-740 , March 2010

The novel synthetic serine protease inhibitor CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model

Read at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery, Boston, Massachusetts, May 9–13, 2009.

  • Gábor Szabó, MD, PhD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    • Corresponding Author InformationAddress for reprints: Gábor Szabó, MD, PhD, Department of Cardiac Surgery, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.
  • ,
  • Gábor Veres, MD

      Affiliations

    • Department of Cardiovascular Surgery, Semmelweis University Medical School, Budapest, Hungary
  • ,
  • Tamás Radovits, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Humaira Haider

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Nelli Krieger

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Susanne Bährle, MD

      Affiliations

    • Department of Cardiology, Angiology and Pulmonology, University of Heidelberg, Heidelberg, Germany
  • ,
  • Silke Niklisch

      Affiliations

    • The Medicine Company, München, Germany
  • ,
  • Christiane Miesel-Gröschel

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Andreas van de Locht, PhD

      Affiliations

    • The Medicine Company, München, Germany
  • ,
  • Matthias Karck, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany

Received 4 May 2009 ,Revised 4 October 2009 ,Accepted 31 October 2009.

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 Disclosures: Andreas van de Locht is an employce of Curacyte, GmbH; Gábor Szabó reports fees and grant support from Curacyte.

PII: S0022-5223(09)01555-4

doi: 10.1016/j.jtcvs.2009.10.059

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 732-740 , March 2010