The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1205-1210 , May 2010

Center variation and outcomes associated with delayed sternal closure after stage 1 palliation for hypoplastic left heart syndrome

  • Jason N. Johnson, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • James Jaggers, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, NC
    • ,
  • Shuang Li, MS

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Sean M. O'Brien, PhD

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Jennifer S. Li, MD, MHS

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Jeffrey P. Jacobs, MD

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, The Congenital Heart Institute of Florida, All Children's Hospital and Children's Hospital of Tampa, University of South Florida College of Medicine, St Petersburg and Tampa, Fla
    • ,
  • Marshall L. Jacobs, MD

      Affiliations

    • Department of Pediatric and Congenital Heart Surgery, Cleveland Clinic, Cleveland, Ohio
    • ,
  • Karl F. Welke, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Ore
    • ,
  • Eric D. Peterson, MD, MPH

      Affiliations

    • Duke Clinical Research Institute, Durham, NC
    • ,
  • Sara K. Pasquali, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • Duke Clinical Research Institute, Durham, NC
    • Corresponding Author InformationReprint requests: Sara K. Pasquali, MD, Assistant Professor of Pediatrics, Division of Cardiology, Department of Pediatrics, Duke University Medical Center, Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715.

Received 23 June 2009 ,Revised 14 October 2009 ,Accepted 14 November 2009.

References 

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  2. McElhinney DB, Reddy VM, Parry AJ, Johnson L, Fineman JR, Hanley FL. Management and outcomes of delayed sternal closure after cardiac surgery in neonates and infants. Crit Care Med. 2000;28:1180–1184
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  5. Riphagen S, McDougall M, Tibby SM, Alphonso N, Anderson D, Austin C, et al. “Early” delayed sternal closure following pediatric cardiac surgery. Ann Thorac Surg. 2005;80:678–684
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  8. Gaynor JW, Mahle WT, Cohen MI, Ittenbach RF, DeCampli WM, Steven JM, et al. Risk factors for mortality after the Norwood procedure. Eur J Cardiothorac Surg. 2002;22:82–89
  9. Forbess JM, Cook N, Roth SJ, Serraf A, Mayer JE, Jonas RA. Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage 1 mortality. Circulation. 1995;92:II262–II266
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  12. Long CB, Shah SS, Lautenbach E, Coffin SE, Tabbutt S, Gaynor JW, et al. Postoperative mediastinitis in children: epidemiology, microbiology and risk factors for gram-negative pathogens. Pediatr Infect Dis J. 2005;24:315–319
  13. Holzmann-Pazgal G, Hopkins-Broyles D, Recktenwald A, Hohrein M, Kieffer P, Huddleston C, et al. Case-control study of pediatric cardiothoracic surgical site infections. Infect Control Hosp Epidemiol. 2008;29:76–79
  14. Levy I, Ovadia B, Erez E, Rinat S, Ashkenazi S, Birk E, et al. Nosocomial infections after cardiac surgery in infants and children: incidence and risk factors. J Hosp Infect. 2003;53:111–116
  15. Curzon CL, Milford-Beland S, Li JS, O'Brien SM, Jacobs JP, Jacobs ML, et al. Cardiac surgery in infants with low birth weight is associated with increased mortality: Analysis of the Society of Thoracic Surgeons Congenital Heart Database. J Thorac Cardiovasc Surg. 2008;135:546–551
  16. Tweddell JS, Hoffman GM, Mussatto KA, Fedderly RT, Berger S, Jaquiss RD, et al. Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: lessons learned from 115 consecutive patients. Circulation. 2002;106(12 Suppl. 1):I82–I89
  17. Mahle WT, Spray TL, Wernovsky G, Gaynor JW, Clark BJ. Survival after reconstructive surgery for hypoplastic left heart syndrome: a 15-year experience from a single institution. Circulation. 2000;102:III136–III141
  18. Tabbutt S, Dominguez TE, Ravishankar C, Marino BS, Gruber PJ, Wernovsky G, et al. Outcomes after the stage I reconstruction comparing the right ventricular to pulmonary artery conduit with the modified Blalock Taussig shunt. Ann Thorac Surg. 2005;80:1582–1590
  19. Azakie T, Merklinger SL, McCrindle BW, Van Arsdell GS, Lee KJ, Benson LN, et al. Evolving strategies and improving outcomes of the modified Norwood procedure: a 10-year single-institution experience. Ann Thorac Surg. 2001;72:1349–1353
  20. Maehara T, Novak I, Wyse RK, Elliot MJ. Perioperative monitoring of total body water by bio-electrical impedance in children undergoing open heart surgery. Eur J Cardiothorac Surg. 1991;5:258–264
  21. Stiller B, Sonntag J, Dähnert I, Alexi-Meskishvili V, Hetzer R, Fischer T, et al. Capillary leak syndrome in children who undergo cardiopulmonary bypass: clinical outcome in comparison with complement activation and C1 inhibitor. Intensive Care Med. 2001;27:193–200
  22. Samir K, Riberi A, Ghez O, Ali M, Metras D, Kreitmann B. Delayed sternal closure: a life-saving measure in neonatal open heart surgery; could it be predictable?. Eur J Cardiothorac Surg. 2002;21:787–793
  23. Glatz JA, Tabbutt S, Gaynor JW, Rome JJ, Montenegro L, Spray TL, et al. Hypoplastic left heart syndrome with atrial level restriction in the era of prenatal diagnosis. Ann Thorac Surg. 2007;84:1633–1638
  24. Owens WA, Vitale N, Hasan A, Hamilton JRL. A policy of elective delayed sternal closure does not improve the outcome after arterial switch. Ann Thorac Surg. 2001;71:1553–1555
  25. Mahle WT, Visconti KJ, Freier C, Kanne SM, Hamilton WG, Sharkey AM, et al. Relationship of surgical approach to neurodevelopmental outcomes in hypoplastic left heart syndrome. Pediatrics. 2006;117:e90–e97

 Disclosures: None.

 Dr Pasquali receives grant support (KL2 RR024127-02) from the National Center for Research Resources, a component of the National Institutes of Health (NIH) and NIH Roadmap for Medical Research, and from the American Heart Association Mid-Atlantic Affiliate Clinical Research Program. The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official view of National Center for Research Resources, NIH, or American Heart Association.

PII: S0022-5223(09)01485-8

doi: 10.1016/j.jtcvs.2009.11.029

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1205-1210 , May 2010

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