The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1183-1188, May 2010

Avoiding cardiopulmonary bypass in extracardiac cavopulmonary connection: Does it really matter?

  • Mohammad Ali Navabi, MD

      Affiliations

    • Department of Pediatric Cardiac Surgery, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran
    • Corresponding Author InformationAddress for reprints: Mohammad Ali Navabi, MD, Department of Pediatric Cardiac Surgery, Imam Hospital, 62 Gharib St, 14194, Tehran, Iran.
  • ,
  • Saideh M. Rastegar, MSN

      Affiliations

    • Department of Pediatric Cardiac Surgery, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Abdolrazagh Kiani, MD

      Affiliations

    • Department of Pediatric Cardiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Mahmood Gholam Ale Mohammad, MD

      Affiliations

    • Department of Pediatric Cardiac Surgery, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Parvin Akbari Asbagh, MD

      Affiliations

    • Department of Pediatric Cardiac Surgery, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Mohammad Reza Mirzaaghayan, MD

      Affiliations

    • Department of Pediatric Cardiac Surgery, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Ali Pasha Meysamie, PhD

      Affiliations

    • Department of Biostatistics, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Reza Shabanian, MD

      Affiliations

    • Department of Pediatric Cardiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Received 29 July 2009; received in revised form 16 September 2009; accepted 16 October 2009. published online 28 December 2009.

Objectives

We examined the effect of avoiding cardiopulmonary bypass on the early outcome variables after fenestrated extracardiac total cavopulmonary connection.

Methods

Between May 2001 and January 2009, 102 patients with univentricular heart physiology underwent fenestrated extracardiac total cavopulmonary connection. Patients were divided into one of 2 groups: the cardiopulmonary bypass (n = 48) group and the no cardiopulmonary bypass (n = 54) group. In both groups there were patients with primary and staged fenestrated extracardiac total cavopulmonary connection. Duration of mechanical ventilation, pleural effusion, hemodynamic status, incidence of arrhythmia, and mortality were compared between the 2 groups.

Results

Both groups were matched, except for more cases of tricuspid atresia in the no cardiopulmonary bypass group (P = .014) compared with other diagnostic morphologies and higher preoperative hemoglobin levels in the no cardiopulmonary bypass group (P = .01). Avoiding cardiopulmonary bypass did not reveal any significant effect on postoperative outcomes. A cardiopulmonary bypass time of more than 120 minutes caused not only a meaningful increase in the mean of mechanical ventilation duration (35 ± 9.6 vs 13 ± 2.1 hours, P = .026) but also increased the incidence of mechanical ventilation for more than 12 hours (P = .04). Bypass time of more than 120 minutes did not have influence on any other postoperative variables.

Conclusion

Avoiding cardiopulmonary bypass in fenestrated extracardiac total cavopulmonary connection had no direct effect on the early outcome variables.

CTSNet classification: 20

Abbreviations and Acronyms: CPB, cardiopulmonary bypass, FECTCPC, fenestrated extracardiac total cavopulmonary connection, ICU, intensive care unit, IVC, inferior vena cava, PA, pulmonary artery, PVR, pulmonary vascular resistance, SVC, superior vena cava, TA, tricuspid atresia, TPG, transpulmonary pressure gradient

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 Disclosures: None.

PII: S0022-5223(09)01396-8

doi:10.1016/j.jtcvs.2009.10.031

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1183-1188, May 2010