The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 793-794 , March 2010

Bleeding complications after off-pump coronary artery bypass surgery: Interpreting the contribution of hetastarch

References 

  1. Hecht-Dolnik M, Barkan H, Taharka A, Loftus J. Hetastarch increases the risk of bleeding complications in patients after off-pump coronary bypass surgery: a randomized clinical trial. J Thorac Cardiovasc Surg. 2009;138:703–711
  2. Kuitunen A, Hynynen M, Salmenperä M, Heinonen J, Vahtera E, Verkkala K, et al. Hydroxyethyl starch as a prime for cardiopulmonary bypass: effects of two different solutions on haemostasis. Acta Anaesthesiol Scand. 1993;37:652–658
  3. Gandhi SD, Weiskopf RB, Jungheinrich C, Koorn R, Miller D, Shangraw RE, et al. Volume replacement therapy during major orthopedic surgery using Voluven (hydroxyethyl starch 130/0.4) or hetastarch. Anesthesiology. 2007;106:1120–1127
  4. Barron ME, Wilkes MM, Navickis RJ. A systematic review of the comparative safety of colloids. Arch Surg. 2004;139:552–563
  5. Wilkes MM, Navickis RJ, Sibbald WJ. Albumin versus hydroxyethyl starch in cardiopulmonary bypass surgery: a meta-analysis of postoperative bleeding. Ann Thorac Surg. 2001;72:527–533
  6. Gan TJ, Bennett-Guerrero E, Phillips-Bute B, Wakeling H, Moskowitz DM, Olufolabi Y, et al. Hextend, a physiologically balanced plasma expander for large volume use in major surgery: a randomized phase III clinical trial. Hextend Study Group. Anesth Analg. 1999;88:992–998
  7. Deusch E, Thaler U, Kozek-Langenecker SA. The effects of high molecular weight hydroxyethyl starch solutions on platelets. Anesth Analg. 2004;99:665–668
  8. Boldt J, Wolf M, Mengistu A. A new plasma-adapted hydroxyethylstarch preparation: in vitro coagulation studies using thrombelastography and whole blood aggregometry. Anesth Analg. 2007;104:425–430
  9. Weeks DL, Jahr JS, Lim JC, Butch AW, Driessen B. Does Hextend impair coagulation compared to 6% hetastarch? An ex vivo thromboelastography study. Am J Ther. 2008;15:225–230
  10. Martin G, Bennett-Guerrero E, Wakeling H, Mythen MG, el-Moalem H, Robertson K, et al. A prospective, randomized comparison of thromboelastographic coagulation profile in patients receiving lactated Ringer's solution, 6% hetastarch in a balanced-saline vehicle, or 6% hetastarch in saline during major surgery. J Cardiothorac Vasc Anesth. 2002;16:441–446
  11. Ahn HJ, Yang M, Gwak MS, Koo MS, Bang SR, Kim GS, et al. Coagulation and biochemical effects of balanced salt-based high molecular weight vs saline-based low molecular weight hydroxyethyl starch solutions during the anhepatic period of liver transplantation. Anaesthesia. 2008;63:235–242
  12. Cabrales P, Tsai AG, Intaglietta M. Resuscitation from hemorrhagic shock with hydroxyethyl starch and coagulation changes. Shock. 2007;28:461–467
  13. Lang K, Boldt J, Suttner S, Haisch G. Colloids versus crystalloids and tissue oxygen tension in patients undergoing major abdominal surgery. Anesth Analg. 2001;93:405–409
  14. Wilkes NJ, Woolf R, Mutch M, Mallett SV, Peachey T, Stephens R, et al. The effects of balanced versus saline-based hetastarch and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients. Anesth Analg. 2001;93:811–816
  15. Villela NR, Vázques BYS, Intaglietta M. Microcirculatory effects of intravenous fluids in critical illness: plasma expansion beyond crystalloids and colloids. Current Opin Anaesthesiol. 2009;22:163–167

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PII: S0022-5223(09)01347-6

doi: 10.1016/j.jtcvs.2009.09.059

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 793-794 , March 2010

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