The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages 1561-1567 , June 2010

The effectiveness of prestorage leukocyte-reduced red blood cell transfusion on perioperative inflammatory response with a miniaturized biocompatible bypass system

Received 25 May 2009 ,Revised 16 August 2009 ,Accepted 3 October 2009.

References 

  1. Seghaye MC, Grabitz RG, Duchateau J, et al. Inflammatory reaction and capillary leak syndrome related to cardiopulmonary bypass in neonates undergoing cardiac operations. J Thorac Cardiovasc Surg. 1996;112:687–697
  2. Ungerleider RM, Shen I. Optimizing response of the neonate and infant to cardiopulmonary bypass. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2003;6:140–146
  3. Ninomiya M, Miyaji K, Takamoto S. Influence of PMEA-coated bypass circuits on perioperative inflammatory response. Ann Thorac Surg. 2003;75:913–918
  4. Miyaji K, Kohira S, Miyamoto T, et al. Pediatric cardiac surgery without homologous blood transfusion, using a miniaturized bypass system in small infants with lower body weight. J Thorac Cardiovasc Surg. 2007;134:284–289
  5. Miyaji K, Miyamoto T, Kohira S, et al. Miniaturized cardiopulmonary bypass system in neonates and small infants. Interact Cardiovasc Thorac Surg. 2008;7:75–78
  6. Mou SS, Giroir BP, Molitor-Kirsch EA, et al. Fresh whole blood versus reconstituted blood for pump priming in heart surgery in infants. N Engl J Med. 2004;351:1635–1644
  7. Buttnerova I, Baumler H, Kern F, et al. Release of WBC-derived IL-1 receptor antagonist into supernatants of RBCs: influence of storage time and filtration. Transfusion. 2001;41:67–73
  8. Sparrow RL, Patton KA. Supernatant from stored red blood cell primes inflammatory cells: influence of prestorage white cell reduction. Transfusion. 2004;44:722–730
  9. Willy C, Reithmeier W, Kuhlmann WD, et al. Leukocyte depletion of red cell components prevents exposure of transfusion recipients to neutrophil elastase. Vox Sang. 2000;78:19–27
  10. Jenkins KJ, Gauvreau K. Center-specific differences in mortality: preliminary analyses using the Risk Adjustment in Congenital Heart Surgery (RACHS-1) method. J Thorac Cardiovasc Surg. 2002;124:97–104
  11. Butler J, Rocker GM, Westaby S. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg. 1993;55:552–559
  12. van Son JA, Hovaguimian H, Rao IM, et al. Strategies for repair of congenital heart defects in infants without the use of blood. Ann Thorac Surg. 1995;59:384–388
  13. Ando M, Takahashi Y, Suzuki N. Open heart surgery for small children without homologous blood transfusion by using remote pump head system. Ann Thorac Surg. 2004;78:1717–1722
  14. Karamlou T, Hickey E, Silliman CC, Shen I, Ungerleider RM. Reducing risk in infant cardiopulmonary bypass: the use of a miniaturized circuit and a crystalloid prime improves cardiopulmonary function and increases cerebral blood flow. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2005;8:3–11
  15. Muylle L, Peetermans ME. Effect of prestorage leukocyte removal on the cytokine levels in stored platelet concentrates. Vox Sang. 1994;66:14–17
  16. Wortham ST, Ortolano GA, Wenz B. A brief history of blood filtration: clot screens, microaggregate removal, and leukocyte reduction. Transfus Med Rev. 2003;17:216–222
  17. Dzik WH. Leukoreduction of blood components. Curr Opin Hematol. 2002;9:521–526
  18. Gruenwald CE, McCrindle BW, Crawford-Lean L, et al. Reconstituted fresh whole blood improves clinical outcomes compared with stored component blood therapy for neonates undergoing cardiopulmonary bypass for cardiac surgery: a randomized controlled trial. J Thorac Cardiovasc Surg. 2008;136:1442–1449

 Disclosures: None.

PII: S0022-5223(09)01344-0

doi: 10.1016/j.jtcvs.2009.10.016

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 6 , Pages 1561-1567 , June 2010