The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2 , Pages 294-301.e1 , February 2010

The Graft Imaging to Improve Patency (GRIIP) clinical trial results

Read at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery (C. Walton Lillehei Resident Forum), Boston, Massachusetts, May 9–13, 2009.

  • Steve K. Singh, MD, MSc

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationAddress for reprints: Steve K. Singh, MD, MSc, c/o Stephen E. Fremes, MD, MSc, 2075 Bayview Ave, Suite H410, Toronto, Ontario, Canada M4 N 3M5.
    • ,
  • Nimesh D. Desai, MD, PhD

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Genta Chikazawa, MD, PhD

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Hiroshi Tsuneyoshi, MD, PhD

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Jessica Vincent, BSc

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Brandon M. Zagorski, MSc

      Affiliations

    • Institute for Clinical Evaluative Science, Toronto, Ontario, Canada
    • ,
  • Visal Pen, MD

      Affiliations

    • Division of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Fuad Moussa, MD, MSc

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Gideon N. Cohen, MD, PhD

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • George T. Christakis, MD, MSc

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Stephen E. Fremes, MD, MSc

      Affiliations

    • Division of Cardiac and Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • Institute for Clinical Evaluative Science, Toronto, Ontario, Canada

Received 8 May 2009 ,Revised 8 September 2009 ,Accepted 28 September 2009.

References 

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  2. FitzGibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR. Coronary bypass graft fate and patient outcome: angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol. 1996;28:616–626
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  8. Puskas JD, Williams WH, Mahoney EM, Huber PR, Block PC, Duke PG, et al. Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. JAMA. 2004;291:1841–1849
  9. Fabricius AM, Gerber W, Hanke M, Garbade J, Autschbach R, Mohr FW. Early angiographic control of perioperative ischemia after coronary artery bypass grafting. Eur J Cardiothorac Surg. 2001;19:853–858
  10. Desai NDD, Miwa S, Kodama D, Cohen G, Christakis GT, Goldman BS, et al. Improving quality of coronary bypass surgery with intraoperative angiography: validation of a new technique. J Am Coll Cardiol. 2005;46:1521–1525
  11. Desai NDD, Miwa S, Kodama D, Koyama T, Cohen G, Pellitier MP, et al. A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg. 2006;132:585–594
  12. Canver CC, Dame NA. Ultrasonic assessment of internal thoracic artery graft flow in the revascularized heart. Ann Thorac Surg. 1994;58:135–138
  13. Morota T, Duhaylongsod FG, Burfeind WR, Huang CT. Intraoperative evaluation of coronary anastomosis by transit-time ultrasonic flow measurement. Ann Thorac Surg. 2002;73:1446–1450
  14. VanHimbergen DJ, Koenig SC, Jaber SF, Cerrito PB, Spence PA. A review of transit-time flow measurement for assessing graft patency. Heart Surg Forum. 1999;2:226–229
  15. MEND-CABG II InvestigatorsAlexander JH, Emery RW, Carrier M, Ellis SJ, Mehta RH, et al. Efficacy and safety of pyridoxal 5′-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: The MEND-CABG II randomized clinical trial. JAMA. 2008;299:1777–1787
  16. Fremes SE, Levinton C, Naylor CD, Chen E, Christakis GT, Goldman BS. Optimal antithrombotic therapy following aortocoronary bypass: a meta-analysis. Eur J Cardiothorac Surg. 1993;7:169–180
  17. Desai NDD, Cohen EA, Naylor CD, Fremes SE. A randomized comparison of radial-artery and saphenous-vein coronary bypass grafts. N Engl J Med. 2004;351:2302–2309
  18. Rousou LJ, Taylor KB, Lu XG, Healey N, Crittenden MD, Khuri SF, et al. Saphenous vein conduits harvested by endoscopic technique exhibit structural and functional damage. Ann Thorac Surg. 2009;87:62–70
  19. Souza DS, Johansson B, Bojö L, Karlsson R, Geijer H, Filbey D, et al. Harvesting the saphenous vein with surrounding tissue for CABG provides long-term graft patency comparable to the left internal thoracic artery: results of a randomized longitudinal trial. J Thorac Cardiovasc Surg. 2006;132:373–378
  20. Balacumaraswami L, Abu-Omar Y, Choudhary B, Pigott D, Taggart D. A comparison of transit-time flowmetry and intraoperative fluorescence imaging for assessing coronary artery bypass graft patency. J Thorac Cardiovasc Surg. 2005;130:315–320

 ClinicalTrials.gov Identifier NCT00187421.

 Disclosures: None.

PII: S0022-5223(09)01283-5

doi: 10.1016/j.jtcvs.2009.09.048

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2 , Pages 294-301.e1 , February 2010

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