The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 1 , Pages e7-e8 , July 2010

Early thrombus in a HeartMate II left ventricular assist device: A potential cause of hemolysis and diagnostic dilemma

  • Castigliano M. Bhamidipati, DO

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia School of Medicine, Charlottesville, Va
    • ,
  • Gorav Ailawadi, MD

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia School of Medicine, Charlottesville, Va
    • ,
  • James Bergin, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Va
    • ,
  • John A. Kern, MD

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia School of Medicine, Charlottesville, Va
    • Corresponding Author InformationAddress for reprints: John A. Kern, MD, Associate Professor of Surgery, Medical Director of Non-Invasive Vascular Laboratory, Department of Surgery, Division of Thoracic and Cardiovascular Surgery, University of Virginia Health System, PO Box 800679, Charlottesville, VA 22908.

Received 11 September 2009 ,Accepted 25 September 2009.

References 

  1. George I, Colley P, Russo MJ, Martens TP, Burke E, Oz MC, et al. Association of device surface and biomaterials with immunologic sensitization after mechanical support. J Thorac Cardiovasc Surg. Jun 2008;135:1372–1379
  2. Meyer AL, Kuehn C, Weidemann J, Malehsa D, Bara C, Fischer S, et al. Thrombus formation in a HeartMate II left ventricular assist device. J Thorac Cardiovasc Surg. 2008;135:203–204
  3. Amir O, Bracey AW, Smart FW, Delgado RM, Shah N, Kar B. A successful anticoagulation protocol for the first HeartMate II implantation in the United States. Tex Heart Inst J. 2005;32(3):399–401
  4. Klovaite J, Gustafsson F, Mortensen SA, Sander K, Nielsen LB. Severely impaired von Willebrand factor-dependent platelet aggregation in patients with a continuous-flow left ventricular assist device (HeartMate II). J Am Coll Cardiol. Jun 2009;53(23):2162–2167
  5. John R, Kamdar F, Liao K, Colvin-Adams M, Miller L, Joyce L, et al. Low thromboembolic risk for patients with the Heartmate II left ventricular assist device. J Thorac Cardiovasc Surg. 2008;136:1318–1323

 Supported by National Institutes of Health Cardiovascular Surgery Research Training Grant T32/HL007849.

 Disclosures: None.

PII: S0022-5223(09)01281-1

doi: 10.1016/j.jtcvs.2009.09.046

The Journal of Thoracic and Cardiovascular Surgery
Volume 140, Issue 1 , Pages e7-e8 , July 2010

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