The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 1 , Pages 181-188, January 2010

Effects of novel synthetic serine protease inhibitors on postoperative blood loss, coagulation parameters, and vascular relaxation after cardiac surgery

  • Gábor Szabó, MD, PhD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    • Corresponding Author InformationAddress for reprints: Gábor Szabó, MD, PhD, Department of Cardiac Surgery, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany.
  • ,
  • Gábor Veres, MD

      Affiliations

    • Department of Cardiology, Angiology, and Pulmonology, University of Heidelberg, Heidelberg, Germany
  • ,
  • Tamás Radovits, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Humaira Haider, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Nelli Krieger, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Susanne Bährle, MD

      Affiliations

    • Department of Cardiovascular Surgery, Semmelweis University Medical School, Budapest, Hungary
  • ,
  • Christiane Miesel-Gröschel, MTA

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Silke Niklisch, MTA

      Affiliations

    • Curacyte Discovery GmbH, Leipzig, Germany
  • ,
  • Matthias Karck, MD

      Affiliations

    • Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
  • ,
  • Andreas van de Locht, PhD

      Affiliations

    • Curacyte Discovery GmbH, Leipzig, Germany

Received 8 May 2008; received in revised form 9 August 2009; accepted 7 September 2009.

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 Read at the Eighty-eighth Annual Meeting of The American Association for Thoracic Surgery, San Diego, Calif, May 10–14, 2008.

 Disclosures: Andreas van de Locht is an employee of Curacyte GmbH; Gábor Szabó reports consulting fees and grant support for this study from Curacyte Ltd, the manufacturer of the analogues.

 Supported by research grant from Curacyte Discovery GmbH, Leipzig, Germany.

PII: S0022-5223(09)01199-4

doi:10.1016/j.jtcvs.2009.09.019

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 1 , Pages 181-188, January 2010