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The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2
, Pages 483-488.e2
, February 2010
Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery
References
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case–control study. Lancet. 2004;364:937–952
- A common allele on chromosome 9 associated with coronary heart disease. Science. 2007;316:1488–1491
- . Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661–678
- Genomewide association analysis of coronary artery disease. N Engl J Med. 2007;357:443–453
- Framingham Heart Study 100 K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet. 2007;8(Suppl 1):S5
- Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation. 2008;117:1675–1684
- . A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science. 2007;316:1491–1493
- Four SNPS on chromosome 9p21 confer risk to premature, familial CAD and MI in an American Caucasian population (GeneQuest). Ann Hum Genet. 2008;72(Pt 5):654–657
- Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9 p. Hum Mol Genet. 2008;17:806–814
- . Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF. Cancer Res. 2007;67:3963–3969
- . The regulation of INK4/ARF in cancer and aging. Cell. 2006;127:265–275
- . Perioperative cardiac events in patients undergoing noncardiac surgery: a review of the magnitude of the problem, the pathophysiology of the events and methods to estimate and communicate risk. CMAJ. 2005;173:627–634
- Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation. 2006;114(1 Suppl):I275–I281
- The MBL2 “LYQA secretor” haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery. Circulation. 2007;116(11 Suppl):I106–I112
- . Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263–265
- Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007;316:1331–1336
- Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions. Arterioscler Thromb Vasc Biol. 2004;24:1391–1396
- INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. PLoS ONE. 2009;4:e5027
- . Synopsis on cellular senescence and apoptosis. J Vasc Surg. 2001;34:173–177
- . Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study. J Am Coll Cardiol. 2008;52:378–384
- . Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have an impact on aneurysmal expansion. Eur J Hum Genet. 2009;17:391–394Epub 2008 Oct 15
- The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet. 2008;40:217–224
- Coronary artery disease–associated locus on chromosome 9p21 and early markers of atherosclerosis. Arterioscler Thromb Vasc Biol. 2008;28:1679–1683
- . Perioperative myocardial infarction—aetiology and prevention. Br J Anaesth. 2005;95:3–19
- Importance of long-duration postoperative ST-segment depression in cardiac morbidity after vascular surgery. Lancet. 1993;341:715–719
- ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol. 2000;36:970–1062
- . Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3. Ann Intern Med. 2009;150:65–72
Disclosures: These studies were supported in part by the Bayer Fellowship in Blood Conservation, Biosite Inc. (San Diego, CA); NIH (HL-068774 and NCRR M01 02558) and a Society of Cardiovascular Anesthesiologists Research Starter Grant.
PII: S0022-5223(09)01090-3
doi: 10.1016/j.jtcvs.2009.06.032
© 2010 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.
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The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2
, Pages 483-488.e2
, February 2010
