The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 1 , Pages 119-127 , January 2010

Evolution of treatment options and outcomes for hypoplastic left heart syndrome over an 18-year period

  • Tara Karamlou, MD

      Affiliations

    • Department of Surgery, Oregon Health & Science University, Portland, Ore
    • Department of Cardiothoracic Surgery, University of Michigan, Ann Arbor, Mich
    • Corresponding Author InformationAddress for reprints: Tara Karamlou, MD, Department of Surgery, L 223, Oregon Health & Science University, 3181 Sam Jackson Park Rd, Portland, OR 97239.
    • ,
  • Brian S. Diggs, PhD

      Affiliations

    • Department of Surgery, Oregon Health & Science University, Portland, Ore
    • ,
  • Ross M. Ungerleider, MD, MPH

      Affiliations

    • Division of Pediatric Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health & Science University, Portland, Ore
    • ,
  • Karl F. Welke, MD, MS

      Affiliations

    • Division of Pediatric Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health & Science University, Portland, Ore

Received 24 June 2008 ,Revised 27 February 2009 ,Accepted 27 April 2009.

References 

  1. Chang RKR, Chen AY, Klitzner TS. Clinical management of infants with hypoplastic left heart syndrome in the United States, 1988–1997. Pediatrics. 2002;110:292–298
  2. Renella P, Chang RKR, Ferry DA, Bart RD, Sklansky MS. Hypoplastic left heart syndrome: attitudes among pediatric residents and nurses toward fetal and neonatal management. Prenat Diagn. 2007;27:1045–1055
  3. Mahle WT, Wernovsky G. Neurodevelopmental outcomes in hypoplastic left heart syndrome. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2004;7:39–47
  4. Gutsegell HP, Gibson J. Management of hypoplastic left heart syndrome in the 1990s. Am J Cardiol. 2002;89:842–846
  5. Gutsegell HP, Massaro TA. Management of Hypoplastic left heart syndrome in a consortium of university hospitals. Am J Cardiol. 1995;76:809–811
  6. Chrisant MRK, Naftel DC, Drummond-Webb J, Chinnock R, Canter CE, Boucek MM, et al. Pediatric Heart Transplant Study Group Fate of infants with hypoplastic left heart syndrome listed for cardiac transplantation: a multicenter study. J Heart Lung Transplant. 2005;24:576–582
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  9. Bailey LL. Transplantation is the best treatment for hypoplastic left heart syndrome. Cardiol Young. 2004;14(Suppl. I):109–111
  10. Elliott A MJ. European perspective on the management of hypoplastic left heart syndrome. Cardiol Young. 2004;14(Suppl. I):41–46
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  12. Jenkins KJ, Gauvreau K, Newburger JW, Spray TL, Moller JH, Iezzonii LI. Consensus-based method for risk adjustment in congenital heart disease. J Thorac Cardiovasc Surg. 2002;123:110–118
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  14. Vlahos AP, Lock JE, McElhinney DB, van der Velde ME. Hypoplastic left heart syndrome with intact or highly restrictive atrial septum. Outcome after neonatal transcatheter atrial septostomy. Circulation. 2004;109:2326–2330
  15. Tworetzky W, McElhinney DB, Reddy VM, Brook MM, Hanley FL, Silverman NH. Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome. Circulation. 2001;103:1269–1273
  16. Mahle WT, Clancy RR, McGaurn SP, Goin JE, Clark BJ. Impact of prenatal diagnosis on survival and early neurologic morbidity in neonates with hypoplastic left heart syndrome. Pediatrics. 2001;107:1277–1282
  17. Rychik J, Rome JJ, Collins MH, DeCampli WM, Spray TL. The hypoplastic left heart syndrome with intact atrial septum: atrial morphology, pulmonary vascular histology and outcome. J Am Coll Cardiol. 1999;34:554–560
  18. Ventura SJTS, Mosher WD, Wilson JB, Henshaw S. Trends in pregnancies and pregnancy termination rates: estimates for the US, 1980—1992. Monthly Vital Statistics Report for NCHS. 1995;43(11 [S]):1–22
  19. Brackley KJ, Kilby MD, Wright JG, Brawn WJ, Sethia B, Stumper O, et al. Outcome after prenatal diagnosis of hypoplastic left heart syndrome: a case series. Lancet. 2000;356:1143–1147
  20. Sharland G, Rollings S, Simpson J, Andrson D. Hypoplastic left heart syndrome. Lancet. 2001;357:722
  21. Vandvik IH, Forde R. Ethical issues in parental decision-making. An interview study of mothers of children with hypoplastic left heart syndrome. Acta Paediatr. 2000;89:1129–1133

 Read at the Thirty-fourth Annual Meeting of The Western Thoracic Surgical Association, Kona, Hawaii, June 25–28, 2008.

PII: S0022-5223(09)01086-1

doi: 10.1016/j.jtcvs.2009.04.061

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 1 , Pages 119-127 , January 2010

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