The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1177-1182 , May 2010

Dextrocardia in patients with Poland syndrome: Phenotypic characterization provides insight into the pathogenesis

  • Michele Torre, MD

      Affiliations

    • Pediatric Surgery Department, Gaslini Children Hospital, Genova, Italy
    • M. Torre and A. Baban contributed equally to this work.
    • Corresponding Author InformationAddress for reprints: Michele Torre, MD, Pediatric Surgery Department, Gaslini Children Hospital, Largo G. Gaslini 5, 16148 Genova-Italy.
    • ,
  • Anwar Baban, MD

      Affiliations

    • Laboratory of Molecular Genetics, Gaslini Children Hospital, Genova, Italy
    • Cardiovascular Department, Gaslini Children Hospital, Genova, Italy
    • M. Torre and A. Baban contributed equally to this work.
    • ,
  • Anna Buluggiu, MD

      Affiliations

    • Pediatric Surgery Department, Gaslini Children Hospital, Genova, Italy
    • ,
  • Sara Costanzo

      Affiliations

    • Pediatric Surgery Department, Gaslini Children Hospital, Genova, Italy
    • ,
  • Lara Bricco, MD

      Affiliations

    • Laboratory of Molecular Genetics, Gaslini Children Hospital, Genova, Italy
    • ,
  • Margherita Lerone, MD

      Affiliations

    • Laboratory of Molecular Genetics, Gaslini Children Hospital, Genova, Italy
    • ,
  • Sebastiano Bianca, MD

      Affiliations

    • Reproductive Genetic Counselling and Teratology Center, Maternal and Infant Department, ARNAS Garibaldi Nesima, Catania, Italy
    • ,
  • Gian Luca Gatti, MD

      Affiliations

    • Plastic and Reconstructive Surgery and Burn Centre Unit, Hospital of Pisa, Pisa, Italy
    • ,
  • Filippo Maria Sénès, MD

      Affiliations

    • Hand Surgery and Microsurgery Unit, Gaslini Children Hospital, Genova, Italy
    • ,
  • Maura Valle, MD

      Affiliations

    • Radiology Unit, Gaslini Children Hospital, Genova, Italy
    • ,
  • Maria Grazia Calevo, PhD

      Affiliations

    • Epidemiology and Biostatistics Service, Scientific Direction, Gaslini Children Hospital, Genova, Italy

Received 31 March 2009 ,Revised 19 July 2009 ,Accepted 10 August 2009.

References 

  1. Poland A. Deficiency of the pectoral muscles. Guy Hosp Rep. 1841;6:191–193
  2. Jones HW. Congenital absence of the pectoral muscles. BMJ. 1926;6:59–60
  3. Lord MJ, Laurenzano KR, Hartmann RW. Poland's syndrome. Clin Pediatr. 1990;29:606–609
  4. Gausewitz SH, Meals RA, Setoguchi Y. Severe limb deficiency in Poland's syndrome. Clin Orthop. 1984;185:9–13
  5. Fraser FC, Teebi A, Walsh S, Pinsky L. Poland sequence with dextrocardia: which comes first?. Am J Med Genet. 1997;73:194–196
  6. Eroglu A, Yildiz D, Tunc H. Dextrocardia is a component of left-sided Poland syndrome. J Thorac Cardiovasc Surg. 2005;130:1471–1472
  7. Mutlu H, Sildiroglu O, Basekim CC, Kizilkaya E. A variant of Poland syndrome associated with dextroposition. J Thorac Imaging. 2007;22:341–342
  8. Cordero García C, Nieto Castilla A, López Jiménez E, Amores García I. Dextrocardia associated with left-sided Poland syndrome. Am J Phys Med Rehabil. 2009;88:168
  9. Hanks SS, Fox V. Dextrocardia associated with Polands syndrome. J Pediatr. 1975;86:312
  10. Pérez Belmonte E, Ochoa Sangrador C, Marugán Isabel V, Casanueva Pascual T, Carrascal Tejado A. Poland's sequence and dextrocardia. An Pediatr (Barc). 2004;61:350–351
  11. Sepulveda W. Poland syndrome: a rare cause of cardiac dextroposition in the fetus. Prenat Diagn. 2009;[Epub ahead of print]
  12. Shamberger R, Welch KJ, Upton J. Surgical treatment of thoracic deformity in Poland's syndrome. J Pediatr Surg. 1989;24:760–766
  13. Bavinck JNB, Weaver DD. Subclavian artery supply disruption sequence hypothesis of a vascular etiology for Poland, Klippel- Feil, and Mobius anomalies. Am J Med Genet. 1986;23:903–918
  14. Assadi FK, Salem M. Poland syndrome associated with renal agenesis. Paediatr Nephrol. 2003;18:307–308
  15. Al-Qattan MM. Classification of hand anomalies in Poland's syndrome. Br J Plast Surg. 2001;54:132–136
  16. Huang SH, Guo L, Song YZ. Neonatal Poland-Moebius syndrome in a case. Zhonghua Er Ke Za Zhi. 2008;46:718–719
  17. Kiratli H, Erdener U. Poland-Moebius syndrome: a case report. Jpn J Ophthalmol. 2000;44:679–682
  18. Cobben JM, van Essen AJ, McParland PC, Polman HA, ten Kate LP. A boy with Poland anomaly and facio-auriculo-vertebral dysplasia. Clin Genet. 1992;41:105–107
  19. Guion-Almeida ML, da Silva Lopes VL. Frontonasal dysplasia, Poland anomaly and unilateral hypoplasia of lower limb: report on a male patient. Clin Dysmorphol. 2003;12:233–236
  20. Shalev SA, Hall JG. Poland anomaly—report of an unusual family. Am J Med Genet. 2003;118A:180–183
  21. Happle R. Poland anomaly may be explained as a paradominant trait. Am J Med Genet. 1999;87:364–365
  22. van Steensel MA. Poland anomaly: not unilateral or bilateral but mosaic. Am J Med Genet A. 2004;125A:211–212
  23. Bohun CM, Potts JE, Casey BM, Sandor GGS. A population-based study of cardiac malformations and outcomes associated with dextrocardia. Am J Cardiol. 2007;100:305–309
  24. Leung AKC, Robson WLM. Dextrocardia with situs solitus. CMAJ. 2006;175:244
  25. Chen JTT. The chest roentgenogram and cardiac fluoroscopy. In:  Alexander RW,  Schlant RC,  Fuster V editor. Hurst's the heart. New York: McGraw-Hill; 1995;p. 387–414

 Disclosures: None.

PII: S0022-5223(09)01078-2

doi: 10.1016/j.jtcvs.2009.08.024

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 5 , Pages 1177-1182 , May 2010

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