The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 543-556 , March 2010

Brain immaturity is associated with brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring

  • Dean B. Andropoulos, MD, MHCM

      Affiliations

    • Department of Anesthesiology, Baylor College of Medicine, Houston, Tex
    • Department of Pediatrics, Baylor College of Medicine, Houston, Tex
    • Division of Pediatric Cardiovascular Anesthesiology, Texas Children's Hospital, Houston, Tex
    • Corresponding Author InformationAddress for reprints: Dean B. Andropoulos, MD, MHCM, Chief of Anesthesiology, Texas Children's Hospital, Professor, Anesthesiology and Pediatrics, Baylor College of Medicine, 6621 Fannin, WT 17417B, Houston, TX 77030.
  • ,
  • Jill V. Hunter, MD

      Affiliations

    • Department of Radiology, Baylor College of Medicine, Houston, Tex
    • Section of Pediatric Neuroradiology, Texas Children's Hospital, Houston, Tex
  • ,
  • David P. Nelson, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Houston, Tex
    • Section of Pediatric Cardiology, Texas Children's Hospital, Houston, Tex
  • ,
  • Stephen A. Stayer, MD

      Affiliations

    • Department of Anesthesiology, Baylor College of Medicine, Houston, Tex
    • Department of Pediatrics, Baylor College of Medicine, Houston, Tex
    • Division of Pediatric Cardiovascular Anesthesiology, Texas Children's Hospital, Houston, Tex
  • ,
  • Ann R. Stark, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Houston, Tex
    • Section of Neonatology, Texas Children's Hospital, Houston, Tex
  • ,
  • E. Dean McKenzie, MD

      Affiliations

    • Department of Surgery, Baylor College of Medicine, Houston, Tex
    • Congenital Heart Surgery Service, Texas Children's Hospital, Houston, Tex
  • ,
  • Jeffrey S. Heinle, MD

      Affiliations

    • Department of Surgery, Baylor College of Medicine, Houston, Tex
    • Congenital Heart Surgery Service, Texas Children's Hospital, Houston, Tex
  • ,
  • Daniel E. Graves, PhD

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Tex
  • ,
  • Charles D. Fraser Jr., MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Houston, Tex
    • Department of Surgery, Baylor College of Medicine, Houston, Tex
    • Congenital Heart Surgery Service, Texas Children's Hospital, Houston, Tex

Received 18 February 2009 ,Revised 16 July 2009 ,Accepted 10 August 2009.

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 Disclosures: Dr Andropoulos is supported in part by NIH National Institute of Child Health and Development grant 1R21 HD055501-01, Baylor College of Medicine General Clinical Research Center Grant #0942, funded by NIH M01 RR00188, and Charles A. Dana Foundation Brain Imaging Grant. The remainder of the funding support was from Texas Children's Hospital Anesthesiology Research Fund, and the Texas Children's Hospital Center for Cardiac Outcomes Research.

PII: S0022-5223(09)01076-9

doi: 10.1016/j.jtcvs.2009.08.022

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 3 , Pages 543-556 , March 2010