The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 6 , Pages 1303-1308 , December 2009

Expression of dual-specificity tyrosine-(Y)-phosphorylation–regulated kinase 2 (DYRK2) can be a favorable prognostic marker in pulmonary adenocarcinoma

Received 1 May 2009 ,Revised 16 July 2009 ,Accepted 7 August 2009.

References 

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  5. Miller CT, Aggarwal S, Lin TK, Dagenais SL, Contreras JI, Orringer MB, et al. Amplification and overexpression of the dual-specificity tyrosine-(Y)- phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinoma. Cancer Res. 2003;63:4136–4143
  6. Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K. DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol Cell. 2007;25:794–796
  7. Pothos A, Plastira K, Plastiras A, Vlachodimitropoulos D, Goutas N, Angelopoulou R. Comparison of chromogenic in situ hybridisation with fluorescence in situ hybridisation and immunohistochemistry for the assessment of her-2/neu oncogene in archival material of breast carcinoma. Acta Histochem Cytochem. 2008;41:59–64
  8. Aarskog NK, Vedeler CA. Real-time quantitative polymerase chain reaction. A new method that detects both the peripheral myelin protein 22 duplication in Charcot–Marie–Tooth type 1A disease and the peripheral myelin protein 22 deletion in hereditary neuropathy with liability to pressure palsies. Hum Genet. 2000;107:494–498
  9. Yoshida K. Role for DYRK family kinases on regulation of apoptosis. Biochem Pharmacol. 2008;76:1389–1394
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  11. Aviel-Ronen S, Coe BP, Lau SK, da Cunha Santos G, Zhu CQ, Strumpf D, et al. Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features. Proc Natl Acad Sci U S A. 2008;105:10155–10160

 Read at the Eighty-ninth Annual Meeting of The American Association for Thoracic Surgery, Boston, Massachusetts, May 9–13, 2009.

PII: S0022-5223(09)01050-2

doi: 10.1016/j.jtcvs.2009.08.003

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 6 , Pages 1303-1308 , December 2009

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