« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2
, Pages 459-465
, February 2010
Impaired angiogenic potency of bone marrow cells from patients with advanced age, anemia, and renal failure
References
- . Long-term efficacy and safety of the intramyocardial implantation of autologous bone marrow cells for the treatment of ischemic heart disease. J Thorac Cardiovasc Surg. 2007;134:1347–1349
- Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet. 2004;364:141–148
- Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med. 2006;355:1210–1221
- Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med. 2006;355:1199–1209
- . Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction. Eur Heart J. 2007;28:766–772
- . Transient increase of cytokines in the acute ischemic tissue is beneficial to cell-based therapeutic angiogenesis. Circ J. 2008;72:2075–2080
- Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circ Res. 2005;97:1142–1151
- Impaired potency of bone marrow mononuclear cells for inducing therapeutic angiogenesis in obese diabetic rats. Am J Physiol Heart Circ Physiol. 2006;290:H1362–H1369
- Impairment in ischemia-induced neovascularization in diabetes: bone marrow mononuclear cell dysfunction and therapeutic potential of placenta growth factor treatment. Am J Pathol. 2004;164:57–66
- Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy. Am J Physiol Heart Circ Physiol. 2005;289:H2089-6
- . Analysis of the origin and population dynamics of cardiac progenitor cells in a donor heart model. Stem Cells. 2007;25:911–917
- . Cellular expression of integrin-beta 1 is of critical importance for inducing therapeutic angiogenesis by cell implantation. Cardiovasc Res. 2005;65:64–72
- Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proc Natl Acad Sci U S A. 2005;102:10999–11004
- . Young adult bone marrow–derived endothelial precursor cells restore aging-impaired cardiac angiogenic function. Circ Res. 2002;90:e89–e93
- Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J Am Coll Cardiol. 2007;49:2341–2349
- . Aging and disease as modifiers of efficacy of cell therapy. Circ Res. 2008;102:1319–1330
- Telomere gap between granulocytes and lymphocytes is a determinant for haematopoetic progenitor cell impairment in patients with previous myocardial infarction. Arterioscler Thromb Vasc Biol. 2008;28:968–974
- Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Circulation. 2007;116:163–173
- Increased total number but impaired migratory activity and adhesion of endothelial progenitor cells in patients on long-term hemodialysis. Am J Kidney Dis. 2004;44:840–849
- Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arterioscler Thromb Vasc Biol. 2004;24:1442–1447
- Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation. 2004;109:1615–1622
- Allogeneic mesenchymal precursor cell therapy to limit remodeling after myocardial infarction: the effect of cell dosage. Ann Thorac Surg. 2009;87:794–801
- Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med. 2003;9:1195–1201
- . Improved angiogenic potency by implantation of ex vivo hypoxia prestimulated bone marrow cells in rats. Am J Physiol Heart Circ Physiol. 2002;283:H468–H473
Disclosures: None.
This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture.
PII: S0022-5223(09)01007-1
doi: 10.1016/j.jtcvs.2009.07.053
© 2010 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2
, Pages 459-465
, February 2010
