The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 4 , Pages 1026-1032 , April 2010

Automatic real-time detection of myocardial ischemia by epicardial accelerometer

  • Per Steinar Halvorsen, MD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • Corresponding Author InformationAddress for reprints: Per Steinar Halvorsen, MD, The Interventional Centre, Rikshospitalet University Hospital, NO-0027 Oslo, Norway.
    • ,
  • Espen W. Remme, MSc, PhD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • ,
  • Andreas Espinoza, MD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • ,
  • Helge Skulstad, MD, PhD

      Affiliations

    • Department of Cardiology, Rikshospitalet University Hospital, Oslo, Norway
    • ,
  • Runar Lundblad, MD, PhD

      Affiliations

    • Department of Cardiothoracic Surgery, Rikshospitalet University Hospital, Oslo, Norway
    • ,
  • Jacob Bergsland, MD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • ,
  • Lars Hoff, MSc, PhD

      Affiliations

    • Faculty of Science and Engineering, Vestfold University College, Horten, Norway
    • ,
  • Kristin Imenes, MSc, PhD

      Affiliations

    • Faculty of Science and Engineering, Vestfold University College, Horten, Norway
    • ,
  • Thor Edvardsen, MD, PhD

      Affiliations

    • Department of Cardiology, Rikshospitalet University Hospital, Oslo, Norway
    • The Faculty of Medicine, University of Oslo, Norway
    • ,
  • Ole Jakob Elle, MD, PhD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • Department of Informatics, University of Oslo, Norway
    • ,
  • Erik Fosse, MD, PhD

      Affiliations

    • The Interventional Centre, Rikshospitalet University Hospital, Oslo, Norway
    • The Faculty of Medicine, University of Oslo, Norway

Received 11 February 2009 ,Revised 8 May 2009 ,Accepted 31 May 2009.

References 

  1. Comunale ME, Body SC, Ley C, Koch C, Roach G, Mathew JP, et al. The concordance of intraoperative left ventricular wall-motion abnormalities and electrocardiographic S-T segment changes: association with outcome after coronary revascularization. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Anesthesiology. 1998;88:945–954
  2. Elle OJ, Halvorsen S, Gulbrandsen MG, Aurdal L, Bakken A, Samset E, et al. Early recognition of regional cardiac ischemia using a 3-axis accelerometer sensor. Physiol Meas. 2005;26:429–440
  3. Halvorsen PS, Espinoza A, Fleischer LA, Elle OJ, Hoff L, Lundblad R, et al. Feasibility of a three-axis epicardial accelerometer in detecting myocardial ischemia in cardiac surgical patients. J Thorac Cardiovasc Surg. 2008;136:1496–1502
  4. Halvorsen PS, Fleischer LA, Espinoza A, Ell OJ, Hoff L, Skulstad H, et al. Detection of myocardial ischaemia by epicardial accelerometers in the pig. Br J Anaesth. 2009;102:29–37
  5. Wood JC, Festen MP, Lim MJ, Buda AJ, Barry DT. Regional effects of myocardial ischemia on epicardially recorded canine first heart sounds. J Appl Physiol. 1994;76:291–302
  6. Imenes K, Aasmundtveit K, Husa EM, Høgetveit JO, Halvorsen PS, Elle OJ, et al. Assembly and packaging of a three-axis micro accelerometer used for detection of heart infarction. Biomed Microdevices. 2007;9:951–957
  7. Hoff L, Elle OJ, Grimnes MJ, Halvorsen S, Alker HJ, Fosse E. Measurements of heart motion using accelerometers. Conf Proc IEEE Eng Med Biol Soc. 2004;3:2049–2051
  8. Hamilton PS, Tompkins WJ. Quantitative investigation of QRS detection rules using the MIT/BIH arrhythmia database. IEEE Trans Biomed Eng. 1986;33:1157–1165
  9. Forrester JS, Tyberg JV, Wyatt HL, Goldner S, Parmely WW, Swan HJ. Pressure-length loop: a new method for simultaneous measurement of segmental and total cardiac function. J Appl Physiol. 1974;37:771–775
  10. D'Ambra MN, Magrassi P, Lowenstein E, Kyo S, Austen WG, Buckley MJ, et al. Myocardial temperature variation: effect on regional function and coronary flow in dogs. Am J Physiol. 1987;252(2 Pt 2):H448–H455
  11. Amundsen BH, Helle-Valle T, Edvardsen T, Torp H, Crosby J, Lyseggen E, et al. Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging. J Am Coll Cardiol. 2006;47:789–793
  12. Edvardsen T, Aakhus S, Endresen K, Bjomerheim R, Smiseth OA, Ihlen H. Acute regional myocardial ischemia identified by 2-dimensional multiregion tissue Doppler imaging technique. J Am Soc Echocardiogr. 2000;13:986–994
  13. Skulstad H, Urheim S, Edvardsen T, Rein KA, Tønnessen TI, Hol PK, et al. Grading of myocardial dysfunction by tissue Doppler echocardiography: a comparison between velocity, displacement, and strain imaging in acute ischemia. J Am Coll Cardiol. 2006;47:1672–1682
  14. Gianrossi R, Detrano R, Mulvihill D, Lehmann K, Dubach P, Colombo A, et al. Exercise-induced ST depression in the diagnosis of coronary artery disease. A meta-analysis. Circulation. 1989;80:87–98

 Disclosures: P.S.H. was recipient of a clinical research fellowship from the Regional Health Authorities. A.E. was a recipient of a clinical research fellowship from the Norwegian Council of Cardio-vascular Diseases. The accelerometer is patented by Rikshospitalet University Hospital; O.J.E., E.F., and P.S.H. are patent holders.

PII: S0022-5223(09)00809-5

doi: 10.1016/j.jtcvs.2009.05.031

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 4 , Pages 1026-1032 , April 2010

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