The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Page 527 , September 2009

Primed for lethal battle: A step forward to enhance the efficacy and efficiency of stem cell transplantation therapy

  • Molly E. Ogle, BS
  • ,
  • Shan Ping Yu, MD, PhD
  • ,
  • Ling Wei, MD

      Affiliations

    • Corresponding Author InformationAddress for reprints: Ling Wei, MD, Professor, Department of Anesthesiology, 101 Woodruff Circle, Emory University School of Medicine, Atlanta, GA 30322.

Received 3 May 2009 ,Accepted 8 June 2009.

References 

  1. Theus MH, Wei L, Cui L, Francis K, Hu X, Keogh C, et al. In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain. Exp Neurol. 2008;210:656–670
  2. Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, Wang JA, et al. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg. 2008;135:799–808
  3. Liu XB, Wang JA, Ogle ME, Wei L. Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival. J Cell Biochem. 2009;106:903–911
  4. Xu H, Ran R, Lu A, Sharp F. Genomic response to hypoxia preconditioning in the adult mouse brain. Abstr Neurosci. 2008;413:6

PII: S0022-5223(09)00799-5

doi: 10.1016/j.jtcvs.2009.06.003

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Page 527 , September 2009