The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Pages 752-759, September 2009

Apyrase treatment prevents ischemia–reperfusion injury in rat lung isografts

  • Seiichiro Sugimoto, MD, PhD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Xue Lin, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Jiaming Lai, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Mikio Okazaki, MD, PhD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Nitin A. Das, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Wenjun Li, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Alexander S. Krupnick, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Ridong Chen, PhD

      Affiliations

    • APT Therapeutics Inc, St Louis, Mo
  • ,
  • Soon Seog Jeong, PhD

      Affiliations

    • APT Therapeutics Inc, St Louis, Mo
  • ,
  • G.A. Patterson, MD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Daniel Kreisel, MD, PhD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
  • ,
  • Andrew E. Gelman, PhD

      Affiliations

    • Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St Louis, Mo
    • Corresponding Author InformationAddress for reprints: Andrew E. Gelman, PhD, Assistant Professor of Surgery, Pathology & Immunology, Campus Box 8234, 660 South Euclid Avenue, Washington University in St Louis, St Louis, MO 63110-1013.

Received 7 November 2008; received in revised form 27 March 2009; accepted 23 April 2009. published online 13 July 2009.

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 This work was sponsored by a NIH SBIR grant (1R42HL087456) from the National Heart, Lung and Blood Institute.

 S. Sugimoto and X. Lin have contributed equally to this work.

PII: S0022-5223(09)00780-6

doi:10.1016/j.jtcvs.2009.04.049

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Pages 752-759, September 2009