The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Pages 538-546.e1 , September 2009

Association of neonatal hypoxia with lasting changes in left ventricular gene expression: An animal model

  • Danny Del Duca, MD

      Affiliations

    • Division of Cardiovascular Surgery, Montréal Children's Hospital—McGill University Health Centre, Montréal, Québec, Canada
    • ,
  • Guoruey Wong, BASc

      Affiliations

    • Department of Physiology, McGill University, Montréal, Québec, Canada
    • ,
  • Phan Trieu, BSc

      Affiliations

    • Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada
    • ,
  • Demetra Rodaros, BSc

      Affiliations

    • Division of Cardiology, Montréal Children's Hospital—McGill University Health Centre, Montréal, Québec, Canada
    • ,
  • Athanasios Kouremenos, BSc

      Affiliations

    • Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada
    • ,
  • Artavazd Tadevosyan, MSc

      Affiliations

    • Department of Medicine, Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Université de Montréal, Montréal, Québec, Canada
    • ,
  • George Vaniotis, BSc

      Affiliations

    • Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Department of Biochemistry, Université de Montréal, Montréal, Québec, Canada
    • Université de Montréal, Montréal, Québec, Canada
    • ,
  • Louis R. Villeneuve, MSc

      Affiliations

    • Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • ,
  • Christo I. Tchervenkov, MD

      Affiliations

    • Division of Cardiovascular Surgery, Montréal Children's Hospital—McGill University Health Centre, Montréal, Québec, Canada
    • ,
  • Stanley Nattel, MD

      Affiliations

    • Department of Medicine, Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Université de Montréal, Montréal, Québec, Canada
    • Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada
    • ,
  • Bruce G. Allen, PhD

      Affiliations

    • Institut de Cardiologie de Montréal, Université de Montréal, Montréal, Québec, Canada
    • Department of Biochemistry, Université de Montréal, Montréal, Québec, Canada
    • Université de Montréal, Montréal, Québec, Canada
    • ,
  • Terence E. Hébert, PhD

      Affiliations

    • Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada
    • Corresponding Author InformationCharles V. Rohlicek, MD, PhD, Department of Cardiology, Montréal Children's Hospital, McGill University Health Centre, 2300 Tupper St, Room D-365, Montréal, Québec, Canada H3H 1P3.
    • ,
  • Charles V. Rohlicek, MD, PhD

      Affiliations

    • Division of Cardiology, Montréal Children's Hospital—McGill University Health Centre, Montréal, Québec, Canada
    • Department of Physiology, McGill University, Montréal, Québec, Canada
    • Department of Pediatrics, McGill University, Montréal, Québec, Canada
    • Corresponding Author InformationAddress for reprints: Terence E. Hébert, PhD, Department of Pharmacology and Therapeutics, McGill University, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler, Room 1303, Montréal, Québec, Canada H3G 1Y6

Received 2 July 2008 ,Revised 1 April 2009 ,Accepted 27 April 2009.

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 Supported by grants from the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Québec (to C.V.R., T.E.H., and S.N.). T.E.H. is a Chercheur National of the Fonds de la Recherche en Santé du Québec, and D.D. holds studentships from the Fonds de la Recherche en Santé du Québec and the Montréal Children's Hospital Research Institute.

 Read at the Thirty-fourth Annual Meeting of The Western Thoracic Surgical Association, Santa Kailua-Kona, Hawaii, June 25–28, 2008.

PII: S0022-5223(09)00766-1

doi: 10.1016/j.jtcvs.2009.04.042

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 3 , Pages 538-546.e1 , September 2009

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