The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4 , Pages 959-964 , October 2009

Prophylactic nesiritide does not prevent dialysis or all-cause mortality in patients undergoing high-risk cardiac surgery

  • A. Ahsan Ejaz, MD

      Affiliations

    • Division of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville, Fla
    • Corresponding Author InformationAddress for reprints: A. Ahsan Ejaz, MD, Division of Nephrology, Hypertension and Transplantation, University of Florida, PO Box 100224, Gainesville, FL 32610-0224.
  • ,
  • Tomas D. Martin, MD

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla
  • ,
  • Richard J. Johnson, MD

      Affiliations

    • Division of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville, Fla
    • Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, Colo
  • ,
  • Almut G. Winterstein, PhD

      Affiliations

    • Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, Fla
  • ,
  • Charles T. Klodell, MD

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla
  • ,
  • Philip J. Hess Jr., MD

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla
  • ,
  • Ayad K. Ali, PharmD

      Affiliations

    • Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, Fla
  • ,
  • Elaine M. Whidden, ARNP

      Affiliations

    • Division of Nephrology, Hypertension and Transplantation, University of Florida, Gainesville, Fla
  • ,
  • Nancy L. Staples, RN

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla
  • ,
  • James A. Alexander, MD

      Affiliations

    • Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver, Colo
  • ,
  • Mary Ann House-Fancher, ARNP

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla
  • ,
  • Thomas M. Beaver, MD, MPH

      Affiliations

    • Division of Thoracic and Cardiothoracic Surgery, University of Florida, Gainesville, Fla

Received 15 September 2008 ,Revised 16 February 2009 ,Accepted 15 May 2009.

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 Disclosures: The study was conducted under an investigator-proposed research grant from Scios, Inc. The authors do not have any other conflict of interest.

 Clinical trials registration:ClinicalTrials.gov NCT00110201.

PII: S0022-5223(09)00712-0

doi: 10.1016/j.jtcvs.2009.05.014

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4 , Pages 959-964 , October 2009