The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 6 , Pages 1358-1362, December 2009

Surgery for acute type A dissection using total arch replacement combined with stented elephant trunk implantation: Experience with 107 patients

  • Li-Zhong Sun, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
    • Corresponding Author InformationAddress for reprints: Li-Zhong Sun, MD, Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, 167 Beilishi Road, Beijing, 100037, China.
  • ,
  • Rui-Dong Qi, MD

      Affiliations

    • Department of Cardiovascular Surgery, Tianjin Cardiovascular Institute and Tianjin Chest Hospital, Tianjin, China
  • ,
  • Qian Chang, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Jun-Ming Zhu, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Yong-Min Liu, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Cun-Tao Yu, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Bin Lv, MD

      Affiliations

    • Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Jun Zheng, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Liang-Xin Tian, MD

      Affiliations

    • Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
  • ,
  • Jin-Guo Lu, MD

      Affiliations

    • Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

Received 19 December 2008; received in revised form 31 March 2009; accepted 17 April 2009. published online 01 June 2009.

Objective

In patients with acute type A dissection, it is controversial whether to use a more aggressive strategy with extended aortic replacement to improve long-term outcome or to use a conventional strategy with limited ascending aortic or hemiarch replacement to circumvent a life-threatening situation.

Methods

Between April 2003 and June 2007, 107 patients (17 women, 90 men; mean age, 45 ± 11 years; range, 17–78 years) with acute type A dissection underwent total arch replacement combined with stented elephant trunk implantation under hypothermic cardiopulmonary bypass and selective cerebral perfusion. Computed tomography was performed to evaluate the residual false lumen in the descending aorta during follow-up.

Results

Thirty-day mortality was 3.74% (4/107 patients), and in-hospital mortality was 4.67% (5/107 patients). Spinal cord injury was observed in 3 patients (1 patient with left lower-extremity paraparesis and 2 patients with paraplegia). Cerebral infarction was observed in 3 patients, ventilator support exceeding 5 days was required in 9 patients, and rebleeding was observed in 4 patients. During a mean follow-up of 35 ± 14 months, 3 patients died and 3 patients were lost to follow-up. On postoperative computed tomography, complete thrombus formation was observed around the stented elephant trunk in 95% of patients (95/100) and at the diaphragmatic level in 69% of patients (69/100).

Conclusion

Low morbidity and mortality were achieved using total arch replacement combined with stented elephant trunk implantation. These encouraging surgical results and postoperative outcomes favor this more aggressive procedure for acute type A dissection.

CTSNet classification: 26

Abbreviations and Acronyms: CPB, cardiopulmonary bypass, CT, computed tomography, SCP, selective cerebral perfusion

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PII: S0022-5223(09)00592-3

doi:10.1016/j.jtcvs.2009.04.017

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 6 , Pages 1358-1362, December 2009