« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4
, Pages 977-984
, October 2009
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury
References
- . Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process. Int J Cardiol. 2005;100:179–190
- . Reperfusion-induced arrhythmias: mechanisms and prevention. J Mol Cell Cardiol. 1984;16:497–518
- . Clinical manifestations of myocardial stunning. Coron Artery Dis. 2001;12:357–361
- . The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusion. Cardiovasc Res. 1996;32:743–751
- Transient release of lipid peroxides after coronary artery balloon angioplasty. Lancet. 1990;336:143–145
- . Influx of neutrophils into the walls of large epicardial coronary arteries in response to ischemia/reperfusion. Circulation. 1991;84:1758–1772
- The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite ‘scavenger’?. J Neurochem. 2004;90:765–768
- Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs. Gastroenterology. 2005;129:1210–1224
- . Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia. J Neurochem. 2007;100:1121–1128
- Oxidative stress-dependent conversion of hydrogen sulfide to sulfite by activated neutrophils. Shock. 2005;24:529–534
- Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun. 2004;318:756–763
- Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. J Appl Physiol. 2007;102:261–268
- . The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. Shock. 2006;26:154–161
- Effects of ischemic preconditioning on myocardial perfusion, function, and microvascular regulation. Circulation. 1998;98:II197–II204discussion II204-5
- . Limitation of reperfusion injury by a monoclonal antibody to C5a during myocardial infarction in pigs. Am J Physiol. 1995;268:H448–H457
- Foxp3-dependent programme of regulatory T-cell differentiation. Nature. 2007;445:771–775
- The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia-reperfusion injury. Eur J Cardiothorac Surg. 2008;33:906–913
- . Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury–Evidence for a role of K ATP channels. Basic Res Cardiol. 2006;101:53–60
- Hydrogen sulfide attenuates myocardial ischemia–reperfusion injury by preservation of mitochondrial function. Proc Natl Acad Sci U S A. 2007;104:15560–15565
- . Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. Faseb J. 2006;20:2118–2120
- . Myocardial protection with potassium-channel openers is as effective as St. Thomas' solution in the rabbit heart. Ann Thorac Surg. 1996;62:31–38discussion 38-9
- . ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart. Curr Vasc Pharmacol. 2003;1:251–258
- . Induction of interleukin-6 synthesis in the myocardium. Potential role in postreperfusion inflammatory injury. Circulation. 1995;92:1866–1875
- Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg. 1994;108:626–635
- Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo. J Clin Invest. 1995;95:89–103
- . Proinflammatory cytokines. Chest. 2000;118:503–508
- . Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res. 2004;94:1543–1553
- . Tumor necrosis factor-alpha: a mediator of disease progression in the failing human heart. Chest. 1999;115:1170–1174
- . Ischemia–reperfusion selectively impairs nitric oxide-mediated dilation in coronary arterioles: counteracting role of arginase. Faseb J. 2003;17:2328–2330
- Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation. 1992;85:1699–1705
- . Management of microvascular dysfunction and reperfusion injury. Heart. 2005;91:1530–1532
- TNF-alpha contributes to endothelial dysfunction in ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol. 2006;26:475–480
- Impact of ST-segment resolution after primary angioplasty on outcomes after myocardial infarction in elderly patients: an analysis from the CADILLAC trial. Am Heart J. 2004;147:669–675
Supported by National Heart, Lung, and Blood Institute grant HL69024-02. N.R.S. and R.T.C. are supported in part by National Institutes of Health grant T-32HL076130-02 and the Irving Bard Memorial Fellowship. Partial funding for this project was provided by Ikaria, Inc, Seattle, Wash.
PII: S0022-5223(09)00565-0
doi: 10.1016/j.jtcvs.2008.08.074
© 2009 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4
, Pages 977-984
, October 2009
