The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 5 , Pages 1200-1205 , November 2009

Reliability of positron emission tomography–computed tomography in identification of mediastinal lymph node status in patients with non–small cell lung cancer

  • Maruf Şanlı, MD

      Affiliations

    • Thoracic Surgery Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • Corresponding Author InformationAddress for reprints: Maruf Şanlı, MD, Gaziantep Üniversitesi, Tıp Fakültesi, Göğüs Cerrahisi AD, 27310-Şehitkamil/Gaziantep/Turkey.
    • ,
  • Ahmet Feridun Isik, MD

      Affiliations

    • Thoracic Surgery Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • ,
  • Sabri Zincirkeser, MD

      Affiliations

    • Nuclear Medicine Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • ,
  • Osman Elbek, MD

      Affiliations

    • Chest Disease Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • ,
  • Ahmet Mete, MD

      Affiliations

    • Radiology Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • ,
  • Bulent Tuncozgur, MD

      Affiliations

    • Thoracic Surgery Department, Gaziantep University, School of Medicine, Gaziantep, Turkey
    • ,
  • Levent Elbeyli, MD

      Affiliations

    • Thoracic Surgery Department, Gaziantep University, School of Medicine, Gaziantep, Turkey

Received 1 September 2008 ,Revised 24 February 2009 ,Accepted 23 March 2009.

References 

  1. Graeter TP, Hellwig D, Hoffmann K, Ukena D, Kirsch CM, Schäfers HJ. Mediastinal lymph node staging in suspected lung cancer: comparison of positron emission tomography with F-18-fluorodeoxyglucose and mediastinoscopy. Ann Thorac Surg. 2003;75:231–235
  2. Roth JA, Atkinson EN, Fossella F, Komaki R, Bernadette Ryan M, Putnam JB, et al. Long-term follow-up of patients enrolled in a randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. Lung Cancer. 1998;21:1–6
  3. Kelly RF, Tran T, Holmstrom A, Murar J, Segurola RJ. Accuracy and cost-effectiveness of [18F]-2-fluoro-deoxy-D-glucose-positron emission tomography scan in potentially resectable non-small cell lung cancer. Chest. 2004;125:1413–1423
  4. Gupta NC, Tamim WJ, Graeber GG, Bishop HA, Hobbs GR. Mediastinal lymph node sampling following positron emission tomography with fluorodeoxyglucose imaging in lung cancer staging. Chest. 2001;120:521–527
  5. Sanli M, Isik AF, Tuncozgur B, Akar E, Deniz H, Bakir K, et al. The reliability of mediastinoscopic frozen sections in deciding on oncological surgery in bronchogenic carcinoma. Adv Ther. 2008;25:488–495
  6. Hellwig D, Graeter TP, Ukena D, Groeschel A, Sybrecht GW, Schaefers HJ, et al. 18F-FDG PET for mediastinal staging of lung cancer: which SUV threshold makes sense?. J Nucl Med. 2007;48:1761–1766
  7. Bryant AS, Cerfolio RJ, Klemm KM, Ojha B. Maximum standard uptake value of mediastinal lymph nodes on integrated FDG-PET-CT predicts pathology in patients with non-small cell lung cancer. Ann Thorac Surg. 2006;82:417–422
  8. Gould MK, Kuschner WG, Rydzak CE, Maclean CC, Demas AN, Shigemitsu H, et al. Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small-cell lung cancer: a meta analysis. Ann Intern Med. 2003;139:879–892
  9. Weng E, Tran L, Rege S, Safa A, Sadeghi A, Juillard G, et al. Accuracy and clinical impact of mediastinal lymph node staging with FDG-PET imaging in potentially resectable lung cancer. Am J Clin Oncol. 2000;23:47–52
  10. Cerfolio RJ, Ojha B, Bryant AS, Raghuveer V, Mountz JM, Bartolucci AA. The accuracy of integrated PET-CT compared with dedicated PET alone for the staging of patients with nonsmall cell lung cancer. Ann Thorac Surg. 2004;78:1017–1023
  11. Eloubeidi MA. Endoscopic ultrasound-guided fine-needle aspiration in the staging and diagnosis of patients with lung cancer. Semin Thorac Cardiovasc Surg. 2007;19:206–211
  12. Eloubeidi MA, Cerfolio RJ, Chen VK, Desmond R, Syed S, Ojha B. Endoscopic ultrasound-guided fine needle aspiration of mediastinal lymph node in patients with suspected lung cancer after positron emission tomography and computed tomography scans. Ann Thorac Surg. 2005;79:263–268
  13. De Leyn P, Lardinois D, Van Schil PE, Rami-Porta R, Passlick B, Zielinski M, et al. ESTS guidelines for preoperative lymph node staging for non-small cell lung cancer. Eur J Cardiothorac Surg. 2007;32:1–8
  14. Herth FJ, Annema JT, Eberhardt R, Yasufuku K, Ernst A, Krasnik M, et al. Endobronchial ultrasound with transbronchial needle aspiration for restaging the mediastinum in lung cancer. J Clin Oncol. 2008;26:3346–3350
  15. Steinert HC, Hauser M, Allemann F, Engel H, Berthold T, von Schulthess GK, et al. Non-small cell lung cancer: nodal staging with FDG PET versus CT with correlative lymph node mapping and sampling. Radiology. 1997;202:441–446
  16. Roberts PF, Follette DM, von Haag D, Park JA, Valk PE, Pounds TR, et al. Factors associated with false-positive staging of lung cancer by positron emission tomography. Ann Thorac Surg. 2000;70:1154–1159
  17. Scott WJ, Schwabe JL, Gupta NC, Dewan NA, Reeb SD, Sugimoto JT. Positron emission tomography of lung tumors and mediastinal lymph nodes using [18F]fluorodeoxyglucose. The Members of the PET-Lung Tumor Study Group. Ann Thorac Surg. 1994;58:698–703

PII: S0022-5223(09)00489-9

doi: 10.1016/j.jtcvs.2009.03.035

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 5 , Pages 1200-1205 , November 2009

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