The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 6 , Pages 1493-1498 , June 2009

Prolonged venoarterial extracorporeal membrane oxygenation after transplantation restores functional integrity of severely injured lung allografts and prevents the development of pulmonary graft failure in a pig model

  • György Lang, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • ,
  • Clemens Aigner, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • ,
  • Günther Winkler, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • ,
  • Keso Shkirdladze, MD

      Affiliations

    • Department of Anaesthesiology, Medical University of Vienna, Vienna, Austria
    • ,
  • Wilfried Wisser, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • ,
  • Gerhard Dekan, MD

      Affiliations

    • Department of Pathology, Medical University of Vienna, Vienna, Austria
    • ,
  • Masaya Tamura, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • ,
  • Georg Heinze, PhD

      Affiliations

    • Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Vienna, Austria
    • ,
  • Dirk Van Raemdonck, MD

      Affiliations

    • Department of Thoracic Surgery, Catholic University Leuven, Leuven, Belgium
    • ,
  • Walter Klepetko, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    • Corresponding Author InformationAddress for reprints: Walter Klepetko, MD, Department of Thoracic Surgery, Medical University of Vienna, Allgemeines Krankenhaus, Währinger Gürtel 18-20, A-1090 Vienna, Austria.

Received 27 August 2008 ,Revised 22 October 2008 ,Accepted 15 November 2008.

  • Image Result

    Mean arterial Pao2 at a fraction of inspired oxygen (Fio2) of 1.0 in function of time. Values are shown as mean levels. BD, Brain death; TP1, time point 1 (immediately after exclusion of the right lun

    Mean arterial Pao2 at a fraction of inspired oxygen (Fio2) of 1.0 in function of time. Values are shown as mean levels. BD, Brain death; TP1, time point 1 (immediately after exclusion of the right lung); TP2, time point 2 (1 hour after exclusion of the right lung); TP3, time point 3 (1 hour after discontinuation of extracorporeal membrane oxygenation).

 Supported by an educational grant from Medtronic.

PII: S0022-5223(09)00352-3

doi: 10.1016/j.jtcvs.2008.11.064

The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 6 , Pages 1493-1498 , June 2009

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