The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4 , Pages 826-830 , October 2009

Asymptomatic congenital cystic adenomatoid malformation of the lung: Is it time to operate?

  • Andrea Conforti, MD

      Affiliations

    • Department of Medical and Surgical Neonatology, Unit of Newborn Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • Corresponding Author InformationAddress for reprints: Andrea Conforti, MD, Department of Medical and Surgical Neonatology, “Bambino Gesu” Children's Hospital, Rome, Italy.
    • ,
  • Ivan Aloi, MD

      Affiliations

    • Department of Surgery, Unit of Pediatric General Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • ,
  • Alessandro Trucchi, MD

      Affiliations

    • Department of Medical and Surgical Neonatology, Unit of Newborn Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • ,
  • Francesco Morini, MD

      Affiliations

    • Department of Medical and Surgical Neonatology, Unit of Newborn Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • ,
  • Antonella Nahom, MD

      Affiliations

    • Department of Medical and Surgical Neonatology, Unit of Newborn Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • ,
  • Alessandro Inserra, MD

      Affiliations

    • Department of Surgery, Unit of Pediatric General Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy
    • ,
  • Pietro Bagolan, MD

      Affiliations

    • Department of Medical and Surgical Neonatology, Unit of Newborn Surgery, “Bambino Gesu” Children's Hospital, Rome, Italy

Received 8 January 2008 ,Revised 17 December 2008 ,Accepted 27 January 2009.

References 

  1. Whitsett JA, Wert SE, Trapnell BC. Genetic disorders influencing lung formation and function at birth. Hum Mol Genet. 2004;13:R207–R215
  2. Gornall AS, Budd JL, Draper ES, Konje JC, Kurinczuk JJ. Congenital cystic adenomatoid malformation: accuracy of prenatal diagnosis, prevalence and outcome in a general population. Prenat Diagn. 2003;23:997–1002
  3. Adzick NS, Harrison MR, Crombleholme TM, Flake AW, Howell LJ. Fetal lung lesions: management and outcome. Am J Obstet Gynecol. 1998;179:884–889
  4. Calvert JK, Boyd PA, Chamberlain PC, Syed S, Lakhoo K. Outcome of antenatally suspected congenital cystic adenomatoid malformation of the lung: 10 years' experience 1991-2001. Arch Dis Child Fetal Neonatal Ed. 2006;91:F26–F28
  5. Kim YT, Kim JS, Park JD, Kang CH, Sung SW, Kim JH. Treatment of congenital cystic adenomatoid malformation-does resection in the early postnatal period increase surgical risk?. Eur J Cardiothorac Surg. 2005;27:658–661
  6. Miller JA, Corteville JE, Langer JC. Congenital cystic adenomatoid malformation in the fetus: natural history and predictors of outcome. J Pediatr Surg. 1996;31:805–808
  7. van Leeuwen K, Teitelbaum DH, Hirschl RB, Austin E, Adelman SH, Polley TZ, et al. Prenatal diagnosis of congenital cystic adenomatoid malformation and its postnatal presentation, surgical indications, and natural history. J Pediatr Surg. 1999;34:794–799
  8. Aziz D, Langer JC, Tuuha SE, Ryan G, Ein SH, Kim PC. Perinatally diagnosed asymptomatic congenital cystic adenomatoid malformation: to resect or not?. J Pediatr Surg. 2004;39:329–334
  9. Calvert JK, Lakhoo K. Antenatally suspected congenital cystic adenomatoid malformation of the lung: postnatal investigation and timing of surgery. J Pediatr Surg. 2007;42:411–414
  10. Sauvat F, Michel JL, Benachi A, Emond S, Revillon Y. Management of asymptomatic neonatal cystic adenomatoid malformations. J Pediatr Surg. 2003;38:548–552
  11. Laberge JM, Flageole H, Pugash D, Khalife S, Blair G, Filiatrault D, et al. Outcome of the prenatally diagnosed congenital cystic adenomatoid lung malformation: a Canadian experience. Fetal Diagn Ther. 2001;16:178–186
  12. Duncombe GJ, Dickinson JE, Kikiros CS. Prenatal diagnosis and management of congenital cystic adenomatoid malformation of the lung. Am J Obstet Gynecol. 2002;187:950–954
  13. Marshall KW, Blane CE, Teitelbaum DH, van Leeuwen K. Congenital cystic adenomatoid malformation: impact of prenatal diagnosis and changing strategies in the treatment of the asymptomatic patient. AJR Am J Roentgenol. 2000;175:1551–1554
  14. Adzick NS, Flake AW, Crombleholme TM. Management of congenital lung lesions. Semin Pediatr Surg. 2003;12:10–16
  15. Aite L, Trucchi A, Nahom A, Zaccara A, La Sala E, Bagolan P. Antenatal diagnosis of surgically correctable anomalies: effects of repeated consultations on parental anxiety. J Perinatol. 2003;23:652–654
  16. Skari H, Malt UF, Bjornland K, Egeland T, Haugen G, Skreden M, et al. Prenatal diagnosis of congenital malformations and parental psychological distress—a prospective longitudinal cohort study. Prenat Diagn. 2006;26:1001–1009
  17. Ozcan C, Celik A, Ural Z, Veral A, Kandiloğlu G, Balik E. Primary pulmonary rhabdomyosarcoma arising within cystic adenomatoid malformation: a case report and review of the literature. J Pediatr Surg. 2001;36:1062–1065

PII: S0022-5223(09)00171-8

doi: 10.1016/j.jtcvs.2009.01.014

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 4 , Pages 826-830 , October 2009

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