The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 5 , Pages 1249-1257 , May 2009

Long-acting oral phosphodiesterase inhibition preconditions against reperfusion injury in an experimental lung transplantation model

  • Eric S. Weiss, MD

      Affiliations

    • Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Md
  • ,
  • Hunter C. Champion, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md
  • ,
  • Jason A. Williams, MD

      Affiliations

    • Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Md
  • ,
  • William A. Baumgartner, MD

      Affiliations

    • Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Md
  • ,
  • Ashish S. Shah, MD

      Affiliations

    • Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Md
    • Corresponding Author InformationAddress for reprints: Ashish S. Shah, MD, Assistant Professor of Surgery, Division of Cardiac Surgery, The Johns Hopkins Hospital, Blalock 618, 600 N. Wolfe St, Baltimore, MD 21287.

Received 13 May 2008 ,Revised 25 November 2008 ,Accepted 30 December 2008.

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 Supported by the Mildred and Carmont Blitz Cardiac Research Fund, the Joyce Koons Family Cardiac Endowment Fund, the American Medical Association Foundation (AMA seed grant, E.S.W.), and the National Institutes of Health (NIH 2T32DK007713-12 ESW). Eric Weiss and Jason Williams are Irene Piccinini Investigators in Cardiac Surgery. The study was also supported in part by an American Heart Association Scientist Development Grant, a grant from the W.W.Smith Charitable Trust, a Shih-Chun Wang Young Investigator Award; a Giles F. Filley Award of the American Physiological Society; the Bernard Family Foundation, and NIHP50HL084946 (H.C.C.).

 Read at the Eighty-eighth Annual Meeting of The American Association for Thoracic Surgery, San Diego, Calif, May 10–14, 2008.

PII: S0022-5223(09)00032-4

doi: 10.1016/j.jtcvs.2008.12.040

The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 5 , Pages 1249-1257 , May 2009