The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 1 , Pages 206-214 , July 2009

The effects of normoxic versus hyperoxic cardiopulmonary bypass on oxidative stress and inflammatory response in cyanotic pediatric patients undergoing open cardiac surgery: A randomized controlled trial

  • Massimo Caputo, MD

      Affiliations

    • Bristol Heart Institute, Bristol, United Kingdom
    • Corresponding Author InformationAddress for reprints: M. Caputo, MD, Bristol Heart Institute, University of Bristol, Bristol Royal Children's Hospital, Bristol, BS2 8HW, United Kingdom.
  • ,
  • Amir Mokhtari, MRCS

      Affiliations

    • Bristol Royal Hospital for Children, Bristol, United Kingdom
  • ,
  • Chris A. Rogers, PhD

      Affiliations

    • Bristol Heart Institute, Bristol, United Kingdom
  • ,
  • Nayia Panayiotou, MSc

      Affiliations

    • Bristol Heart Institute, Bristol, United Kingdom
  • ,
  • Qiang Chen, PhD

      Affiliations

    • Bristol Royal Hospital for Children, Bristol, United Kingdom
  • ,
  • Mohamed T. Ghorbel, PhD

      Affiliations

    • Bristol Heart Institute, Bristol, United Kingdom
  • ,
  • Gianni D. Angelini, FRCS

      Affiliations

    • Bristol Heart Institute, Bristol, United Kingdom
  • ,
  • Andrew J. Parry, FRCS

      Affiliations

    • Bristol Royal Hospital for Children, Bristol, United Kingdom

Received 19 September 2008 ,Revised 21 November 2008 ,Accepted 25 December 2008.

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 The BUPA Foundation, National Heart Research Fund, Garfield Weston Trust, and the British Heart Foundation supported this work.

 All participants in this study have seen and approved the final version and have no conflicts of interest to disclose.

PII: S0022-5223(09)00018-X

doi: 10.1016/j.jtcvs.2008.12.028

The Journal of Thoracic and Cardiovascular Surgery
Volume 138, Issue 1 , Pages 206-214 , July 2009