The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 3 , Pages 560-564 , March 2009

Fontan hemodynamics: Importance of pulmonary artery diameter

  • Lakshmi P. Dasi, PhD

      Affiliations

    • Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga
    • Contributed equally.
    • ,
  • Resmi KrishnankuttyRema, MS

      Affiliations

    • Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga
    • Contributed equally.
    • ,
  • Hiroumi D. Kitajima, PhD

      Affiliations

    • Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga
    • ,
  • Kerem Pekkan, PhD

      Affiliations

    • Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga
    • Currently working in the Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pa.
    • ,
  • Kartik S. Sundareswaran, MS

      Affiliations

    • Children's Healthcare of Atlanta, Atlanta, Ga
    • ,
  • Mark Fogel, MD

      Affiliations

    • Children's Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Shiva Sharma, MD

      Affiliations

    • Pediatric Cardiology Services, Lawrenceville, Ga
    • ,
  • Kevin Whitehead, MD, PhD

      Affiliations

    • Children's Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Kirk Kanter, MD

      Affiliations

    • Children's Healthcare of Atlanta, Atlanta, Ga
    • Emory University School of Medicine, Atlanta, Ga
    • ,
  • Ajit P. Yoganathan, PhD

      Affiliations

    • Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga
    • Corresponding Author InformationAddress for reprints: Ajit P. Yoganathan, PhD, Wallace H. Coulter School of Biomedical Engineering, Georgia Institute of Technology, Room 2119 U.A. Whitaker Building, 313 First Dr. Atlanta, GA 30332-0535.

Received 30 November 2007 ,Revised 29 February 2008 ,Accepted 4 April 2008.

  • Image Result

    Mean cross-sectional areas of each vessel in the vicinity of the TCPC compared between EC and LT patient groups (n = 11 each). IVC, Inferior vena cava; SVC, superior vena cava; RPA, right pulmonary ar

    Mean cross-sectional areas of each vessel in the vicinity of the TCPC compared between EC and LT patient groups (n = 11 each). IVC, Inferior vena cava; SVC, superior vena cava; RPA, right pulmonary artery; LPA, left pulmonary artery; BSA, body surface area.

  • Image Result
    Minimum cross-sectional areas computed between the TCPC outlet vessels left and right pulmonary arteries for EC and LT patient groups (n = 11 each). PA, Pulmonary artery; BSA, body surface area.

    Minimum cross-sectional areas computed between the TCPC outlet vessels left and right pulmonary arteries for EC and LT patient groups (n = 11 each). PA, Pulmonary artery; BSA, body surface area.

  • Image Result
    Normalized TCPC power loss obtained from in vitro experiments and CFD simulations computed at the physiologic conditions plotted against the minimum cross-sectional areas of the pulmonary arteries (P

    Normalized TCPC power loss obtained from in vitro experiments and CFD simulations computed at the physiologic conditions plotted against the minimum cross-sectional areas of the pulmonary arteries (PA). BSA, Body surface area.

  • Image Result
    Normalized minimum cross-sectional areas of the pulmonary arteries (PA) plotted against the patient cardiac index. BSA, Body surface area.

    Normalized minimum cross-sectional areas of the pulmonary arteries (PA) plotted against the patient cardiac index. BSA, Body surface area.

 Funded by the National Heart, Lung, and Blood Institute (HL67622).

PII: S0022-5223(08)01946-6

doi: 10.1016/j.jtcvs.2008.04.036

The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 3 , Pages 560-564 , March 2009

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