The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 6 , Pages 1515-1520 , June 2009

Plasma transforming growth factor β1 as a biochemical marker to predict the persistence of atrial fibrillation after the surgical maze procedure

  • Young Keun On, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • Eun-Seok Jeon, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • Corresponding Author InformationAddress for reprints: Eun-Seok Jeon, MD, PhD, Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Kangnam-gu, 135-710, Seoul, Korea.
    • ,
  • Sang Yeub Lee, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • Dae-Hee Shin, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • Jin-Oh Choi, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • Jidong Sung, MD, MPH

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • June Soo Kim, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Medicine, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • Kiick Sung, MD

      Affiliations

    • Department of Thoracic and Cardiovascular Surgery, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    • ,
  • PyoWon Park, MD, PhD

      Affiliations

    • Department of Thoracic and Cardiovascular Surgery, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Received 10 July 2008 ,Revised 17 September 2008 ,Accepted 16 October 2008.

  • Image Result

    Comparisons of the areas of fibrosis in the left atrium among groups. Collagen is stained in blue in Masson trichrome staining (A-C) and red in Sirius red staining (D-F) in the left atrium of the sinu

    Comparisons of the areas of fibrosis in the left atrium among groups. Collagen is stained in blue in Masson trichrome staining (A-C) and red in Sirius red staining (D-F) in the left atrium of the sinus rhythm group (A and D), the atrial fibrillation to sinus rhythm group (B and E), and the atrial fibrillation group (C and F). (Original magnification ×100.)

  • Image Result
    Correlation between transforming growth factor (TGF) β1 level and the degree of fibrosis. The plasma TGF-β1 level was correlated with the degree of fibrosis (r = 0.497, P = .022).

    Correlation between transforming growth factor (TGF) β1 level and the degree of fibrosis. The plasma TGF-β1 level was correlated with the degree of fibrosis (r = 0.497, P = .022).

PII: S0022-5223(08)01737-6

doi: 10.1016/j.jtcvs.2008.10.022

The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 6 , Pages 1515-1520 , June 2009

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