The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 1 , Pages 36-42 , January 2009

Health-related quality of life in esophageal cancer: Effect of neoadjuvant chemoradiotherapy followed by surgical intervention

  • Najib Safieddine, MD

      Affiliations

    • Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Wei Xu, PhD

      Affiliations

    • Department of Biostatistics, Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Sayed Mohammed Quadri, MD, FRCSC

      Affiliations

    • Division of Thoracic Surgery, University of British Columbia, Vancouver, British Columbia, Canada
    • ,
  • Jennifer J. Knox, MD, FRCP

      Affiliations

    • Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Jennifer Hornby, BSc, CCRP

      Affiliations

    • Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Joanne Sulman, MSW

      Affiliations

    • Department of Social Work, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Rebecca Wong, MD, FRCP

      Affiliations

    • Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Maha Guindi, MD, FRCP

      Affiliations

    • Department of Pathology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Shaf Keshavjee, MD, MSc, FRCSC, FACS

      Affiliations

    • Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Gail Darling, MD, FRCSC, FACS

      Affiliations

    • Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationAddress for reprints: Gail Darling, MD, FRCSC, FACS, Toronto General Hospital, Division of Thoracic Surgery, 9N-955, 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada.

Received 29 March 2007 ,Revised 24 September 2008 ,Accepted 30 September 2008.

  • Image Result

    Number of patients versus waiting time between neoadjuvant treatment and surgical intervention.

    Number of patients versus waiting time between neoadjuvant treatment and surgical intervention.

  • Image Result

    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time: patients alive at 1 year (n = 33). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy;

    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time: patients alive at 1 year (n = 33). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

  • Image Result
    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time: died before 1 year (n = 17). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx

    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time: died before 1 year (n = 17). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

  • Image Result
    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time (n = 50). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection;

    Mean Functional Assessment of Cancer Therapy–Esophageal (FACT-[E]) scores versus time (n = 50). Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

  • Image Result
    Physical well-being scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

    Physical well-being scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

  • Image Result
    Functional well-being scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

    Functional well-being scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

  • Image Result
    Esophageal subscale scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

    Esophageal subscale scores. Pretx, Before treatment; neo, 7 weeks after initiation of neoadjuvant therapy; presx, before resection; postsx, after resection.

 Read at the Eighty-seventh Annual Meeting of The American Association for Thoracic Surgery, Washington, DC, May 5–9, 2007.

PII: S0022-5223(08)01647-4

doi: 10.1016/j.jtcvs.2008.09.049

The Journal of Thoracic and Cardiovascular Surgery
Volume 137, Issue 1 , Pages 36-42 , January 2009

Article Tools

* Image Usage & Resolution