The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2 , Pages e6-e7 , February 2010

Heparin-induced thrombosis without thrombocytopenia

  • Frederick A. Tibayan, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif
    • ,
  • Lawrence L. Leung, MD

      Affiliations

    • Department of Medicine, Division of Hematology, Stanford University, Stanford, Calif
    • Section of Hematology, VA Palo Alto HCS, Palo Alto, Calif
    • ,
  • Thomas A. Burdon, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif
    • Cardiothoracic Surgery, VA Palo Alto HCS, Palo Alto, Calif
    • ,
  • James I. Fann, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Stanford University, Stanford, Calif
    • Cardiothoracic Surgery, VA Palo Alto HCS, Palo Alto, Calif
    • Corresponding Author InformationAddress for reprints: James I. Fann, MD, 300 Pasteur Drive, Stanford, CA 94305-5247.

Received 4 June 2008 ,Accepted 4 July 2008.

References 

  1. Selleng S, Seleng K, Wollert HG, Muellejans B, Lietz T, Warkentin TE, et al. Heparin-induced thrombocytopenia in patients requiring prolonged intensive care unit treatment after cardiopulmonary bypass. J Thromb Haemost. 2008;6:428–435
  2. Greinacher A, Farner B, Kroll H, Kohlmann T, Warkentin TE, Eichler P. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients. Thromb Haemost. 2005;94:132–135
  3. Pouplard C, May MA, Regina S, Marchand M, Fusciardi J, Gruel Y. Changes in platelet count after cardiac surgery can effectively predict the development of pathogenic heparin-dependent antibodies. Br J Haematol. 2005;128:837–841
  4. Warkentin TE, Roberts RS, Hirsh J, Kelton JG. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch Intern Med. 2003;163:2518–2524
  5. Warkentin TE, Greinacher A. Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:311S–337S

 Disclosures: None.

PII: S0022-5223(08)01176-8

doi: 10.1016/j.jtcvs.2008.07.006

The Journal of Thoracic and Cardiovascular Surgery
Volume 139, Issue 2 , Pages e6-e7 , February 2010

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