The Journal of Thoracic and Cardiovascular Surgery
Volume 136, Issue 5 , Pages 1149-1155 , November 2008

Influence of preoperative renal dysfunction on one-year bypass graft patency and two-year outcomes in patients undergoing coronary artery bypass surgery

  • Rajendra H. Mehta, MD, MS

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • Corresponding Author InformationAddress for reprints: Rajendra H. Mehta, MD, MS, Box 17969, Duke Clinical Research Institute, Durham, NC 27715.
    • ,
  • Gail E. Hafley, MS

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • ,
  • C. Michael Gibson, MD

      Affiliations

    • Beth Israel Deaconess Medical Center, Boston, Mass
    • ,
  • Robert A. Harrington, MD

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • ,
  • Eric D. Peterson, MD, MPH

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • ,
  • Michael J. Mack, MD

      Affiliations

    • Medical City Hospital, Dallas, Tex
    • ,
  • Nicholas T. Kouchoukos, MD

      Affiliations

    • Missouri Baptist Medical Center, St Louis, Mo
    • ,
  • Robert M. Califf, MD

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • ,
  • T. Bruce Ferguson Jr., MD

      Affiliations

    • East Carolina University, Greenville, NC
    • ,
  • John H. Alexander, MD, MHS

      Affiliations

    • Duke Clinical Research Institute and Duke University Medical Center, Durham, NC
    • ,
  • Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT)-IV Investigators

Received 21 August 2007 ,Revised 12 December 2007 ,Accepted 19 February 2008.

References 

  1. Cooper WA, O'Brien SM, Thourani VH, et al. Impact of renal dysfunction on outcomes of coronary bypass surgery: results from the Society of Thoracic Surgery National Adult Cardiac Database. Circulation. 2006;113:1063–1070
  2. Reddan DN, Szczech L, Tuttle RH, et al. Chronic kidney disease, mortality and treatment strategies among patients with clinically significant coronary artery disease. J Am Soc Nephrol. 2003;14:2373–2380
  3. Szczech LA, Reddan DN, Owen WF, et al. Differential survival following coronary revascularization procedures among patients with renal insufficiency. Kidney Int. 2001;60:292–299
  4. Wilson S, Foo K, Cunningham J, et al. Renal function and risk stratification in acute coronary syndromes. Am J Cardiol. 2003;91:1051–1054
  5. Alexander JH, Ferguson TB, Joseph DM, et al. The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics. Am Heart J. 2005;150:643–649
  6. The PREVENT IV Investigators. Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery-PREVENT IV: a randomized controlled trial. JAMA. 2005;294:2446–2454
  7. Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31–41
  8. Joki N, Hase H, Nakamura R, et al. Onset of coronary artery disease prior to initiation of hemodialysis in patients with end-stage renal disease. Nephrol Dial Transplant. 1997;12:718–723
  9. Levey AS, Beto JA, Coronado BE, et al. Controlling the epidemic of cardiovascular disease in chronic renal disease: What do we know? What do we need to learn? Where do we go from here? National Kidney Foundation Task Force on Cardiovascular Disease. Am J Kidney Dis. 1998;32:853–906
  10. Mehta RH, Grab JD, O'Brien SM, et al. Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery. Circulation. 2006;114:2208–2216
  11. Keeley EC, Kadakia R, Soman S, Borzak S, McCullough PA. Analysis of long-term survival after revascularization in patients with chronic kidney disease presenting with acute coronary syndromes. Am J Cardiol. 2003;92:509–514
  12. Hemmelgarn BR, Southern D, Culleton BF, Mitchell LB, Knudtson ML, Ghali WA. Survival after coronary revascularization among patients with kidney disease. Circulation. 2004;110:1890–1895
  13. Rinehart AL, Herzog CA, Collins AJ, Flack JM, Ma JZ, Opsahl JA. A comparison of coronary angiography and coronary artery bypass grafting outcomes in chronic dialysis dependent renal failure patients. Am J Kidney Dis. 1995;25:281–290
  14. Khan JK, Rutherford BD, McConahay DR, Johnson WL, Giorgi LV, Hartzler GO. Short- and long-term outcome of percutaneous transluminal coronary angioplasty in chronic dialysis patients. Am Heart J. 1990;119:484–489
  15. Herzog CA, Ma JZ, Collins AJ. Comparative survival of dialysis patients in United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetes. Circulation. 2002;106:2207–2211
  16. Szczech LA, Best PJ, Crowley E, et al. Outcomes of patients with chronic renal insufficiency in the Bypass Angioplasty Revascularization Investigation. Circulation. 2002;105:2253–2258
  17. McCullough PA. Cardiorenal risk: an important clinical intersection. Rev Cardiovasc Med. 2002;3:71–76
  18. Loop FD, Lytle BW, Cosgrove DM, et al. Influence of the internal mammary artery graft on 10 year survival and other cardiac events. N Engl J Med. 1986;314:1–6
  19. Hannan EL, Kilburn H, Racz M, Shields EP, Chasin MR. Improving the outcomes of coronary artery bypass surgery in New York State. JAMA. 1994;271:761–766

 The Prevent-IV trial was funded by Corgentech Inc, South San Francisco, Calif. Dr Mehta is funded by the Duke Clinical Research Institute, Durham, NC.

PII: S0022-5223(08)01090-8

doi: 10.1016/j.jtcvs.2008.02.085

The Journal of Thoracic and Cardiovascular Surgery
Volume 136, Issue 5 , Pages 1149-1155 , November 2008

Article Tools

* Image Usage & Resolution