The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 739-745 , April 2008

Glycemic profile in infants who have undergone the arterial switch operation: Hyperglycemia is not associated with adverse events

  • Joseph W. Rossano, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • Corresponding Author InformationAddress for reprints: Joseph W. Rossano, MD, Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children's Hospital, 6621 Fannin MC 19345-C, Houston, TX 77030.
    • ,
  • Michael D. Taylor, MD, PhD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • ,
  • E. O'Brian Smith, PhD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • ,
  • Charles D. Fraser Jr., MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex
    • ,
  • E. Dean McKenzie, MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex
    • ,
  • Jack F. Price, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • ,
  • Heather A. Dickerson, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • ,
  • David P. Nelson, MD, PhD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex
    • ,
  • Antonio R. Mott, MD

      Affiliations

    • Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Tex

Received 1 September 2007 ,Revised 12 October 2007 ,Accepted 5 November 2007.

References 

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  3. Malmberg K. Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study Group. BMJ. 1997;314:1512–1515
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  5. Ouattara A, Lecomte P, Le Manach Y, Landi M, Jacqueminet S, Platonov I, et al. Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients. Anesthesiology. 2005;103:687–694
  6. Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, Williams BA, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clin Proc. 2005;80:862–866
  7. van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345:1359–1367
  8. Whitcomb BW, Pradhan EK, Pittas AG, Roghmann MC, Perencevich EN. Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations. Crit Care Med. 2005;33:2772–2777
  9. Freire AX, Bridges L, Umpierrez GE, Kuhl D, Kitabchi AE. Admission hyperglycemia and other risk factors as predictors of hospital mortality in a medical ICU population. Chest. 2005;128:3109–3116
  10. de Ferranti S, Gauvreau K, Hickey PR, Jonas RA, Wypij D, du Plessis A, et al. Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4, and 8 years. Anesthesiology. 2004;100:1345–1352
  11. Lopaschuk GD, Collins-Nakai RL, Itoi T. Developmental changes in energy substrate use by the heart. Cardiovasc Res. 1992;26:1172–1180
  12. Van den Berghe G, Wouters PJ, Bouillon R, Weekers F, Verwaest C, Schetz M, et al. Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control. Crit Care Med. 2003;31:359–366
  13. Vannucci RC, Vannucci SJ. Hypoglycemic brain injury. Semin Neonatol. 2001;6:147–155
  14. Steinkrauss L, Lipman TH, Hendell CD, Gerdes M, Thornton PS, Stanley CA. Effects of hypoglycemia on developmental outcome in children with congenital hyperinsulinism. J Pediatr Nurs. 2005;20:109–118
  15. Hoerter J. Changes in the sensitivity to hypoxia and glucose deprivation in the isolated perfused rabbit heart during perinatal development. Pflugers Arch. 1976;363:1–6
  16. Yacoub MH, Radley-Smith R. Anatomy of the coronary arteries in transposition of the great arteries and methods for their transfer in anatomical correction. Thorax. 1978;33:418–424
  17. Dibardino DJ, Allison AE, Vaughn WK, McKenzie ED, Fraser CD. Current expectations for newborns undergoing the arterial switch operation. Ann Surg. 2004;239:588–596
  18. Finney SJ, Zekveld C, Elia A, Evans TW. Glucose control and mortality in critically ill patients. JAMA. 2003;290:2041–2047
  19. Jakob SM, Ensinger H, Takala J. Metabolic changes after cardiac surgery. Curr Opin Clin Nutr Metab Care. 2001;4:149–155
  20. Raghavan M, Marik PE. Stress hyperglycemia and adrenal insufficiency in the critically ill. Semin Respir Crit Care Med. 2006;27:274–285
  21. Yates AR, Dyke PC, Taeed R, Hoffman TM, Hayes J, Feltes TF, et al. Hyperglycemia is a marker for poor outcome in the postoperative pediatric cardiac patient. Pediatr Crit Care Med. 2006;7:351–355
  22. Hansen TK, Thiel S, Wouters PJ, Christiansen JS, Van den Berghe G. Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab. 2003;88:1082–1088
  23. Vanhorebeek I, De Vos R, Mesotten D, Wouters PJ, De Wolf-Peeters C, Van den Berghe G. Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet. 2005;365:53–59
  24. Parrillo JE. Severe sepsis and therapy with activated protein C. N Engl J Med. 2005;353:1398–1400

PII: S0022-5223(07)01945-9

doi: 10.1016/j.jtcvs.2007.11.030

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 739-745 , April 2008

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