The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 746-753 , April 2008

Perioperative B-type natriuretic peptide levels predict outcome after bidirectional cavopulmonary anastomosis and total cavopulmonary connection

  • Jong-Hau Hsu, MD

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
    • Department of Pediatrics, Kaohsiung Medical University, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
  • ,
  • Peter E. Oishi, MD

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
  • ,
  • Roberta L. Keller, MD

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
  • ,
  • Omar Chikovani, MD

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
  • ,
  • Tom R. Karl, MD

      Affiliations

    • Department of Surgery, University of California, San Francisco, Calif
  • ,
  • Anthony Azakie, MD

      Affiliations

    • Department of Surgery, University of California, San Francisco, Calif
  • ,
  • Ian Adatia, MBChB

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
  • ,
  • Jeffrey R. Fineman, MD

      Affiliations

    • Department of Pediatrics, University of California, San Francisco, Calif
    • Cardiovascular Research Institute, University of California, San Francisco, Calif
    • Corresponding Author InformationAddress for reprints: Jeffrey R. Fineman, MD, Department of Pediatrics, UCSF Medical Center, 513 Parnassus Avenue, Box 0106, San Francisco, CA 94143.

Received 30 August 2007 ,Revised 5 October 2007 ,Accepted 31 October 2007.

References 

  1. Scheurer MA, Hill EG, Vasuki N, Maurer S, Graham EM, Bandisode V, et al. Survival after bidirectional cavopulmonary anastomosis: analysis of preoperative risk factors. J Thorac Cardiovasc Surg. 2007;134:82–8989.e1-2
  2. Mahle WT, Cohen MS, Spray TL, Rychik J. Atrioventricular valve regurgitation in patients with single ventricle: impact of the bidirectional cavopulmonary anastomosis. Ann Thorac Surg. 2001;72:831–835
  3. Alejos JC, Williams RG, Jarmakani JM, Galindo AJ, Isabel-Jones JB, Drinkwater D, et al. Factors influencing survival in patients undergoing the bidirectional Glenn anastomosis. Am J Cardiol. 1995;75:1048–1050
  4. Gentles TL, Mayer JE, Gauvreau K, Newburger JW, Lock JE, Kupferschmid JP, et al. Fontan operation in five hundred consecutive patients: factors influencing early and late outcome. J Thorac Cardiovasc Surg. 1997;114:376–391
  5. Hosein RB, Clarke AJ, McGuirk SP, Griselli M, Stumper O, De Giovanni JV, et al. Factors influencing early and late outcome following the Fontan procedure in the current era. The ‘Two Commandments’?. Eur J Cardiothorac Surg. 2007;31:344–353
  6. Sudoh T, Kangawa K, Minamino N, Matsuo H. A new natriuretic peptide in porcine brain. Nature. 1988;332:78–81
  7. Levin ER, Gardner DG, Samson WK. Natriuretic peptides. N Engl J Med. 1998;339:321–328
  8. Hsu J, Keller R, Chikovani O, Cheng H, Hollander S, Karl T, et al. B-type natriuretic peptide levels predict outcome after neonatal cardiac surgery. J Thorac Cardiovasc Surg. 2007;134:939–945
  9. Cannesson M, Bionda C, Gostoli B, Raisky O, di Filippo S, Bompard D, et al. Time course and prognostic value of plasma B-type natriuretic peptide concentration in neonates undergoing the arterial switch operation. Anesth Analg. 2007;104:1059–1065tables of contents
  10. Shih CY, Sapru A, Oishi P, Azakie A, Karl TR, Harmon C, et al. Alterations in plasma B-type natriuretic peptide levels after repair of congenital heart defects: a potential perioperative marker. J Thorac Cardiovasc Surg. 2006;131:632–638
  11. Chikovani O, Hsu J, Keller R, Karl T, Azakie A, Adatia I, et al. B-type natriuretic peptide levels predict outcomes for children on extracorporeal life support after cardiac surgery. J Thorac Cardiovasc Surg. 2007;134:1179–1187
  12. Hoffman TM, Wernovsky G, Atz AM, Kulik TJ, Nelson DP, Chang AC, et al. Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation. 2003;107:996–1002
  13. Wernovsky G, Wypij D, Jonas RA, Mayer JE, Hanley FL, Hickey PR, et al. Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation. 1995;92:2226–2235
  14. Day RW, Orsmond GS, Sturtevant JE, Hawkins JA, Doty DB, McGough EC. Early and intermediate results of the Fontan procedure at moderately high altitude. Ann Thorac Surg. 1994;57:170–176
  15. Sun LS, Dominguez C, Mallavaram NA, Quaegebeur JM. Dysfunction of atrial and B-type natriuretic peptides in congenital univentricular defects. J Thorac Cardiovasc Surg. 2005;129:1104–1110
  16. Ationu A, Singer DR, Smith A, Elliott M, Burch M, Carter ND. Studies of cardiopulmonary bypass in children: implications for the regulation of brain natriuretic peptide. Cardiovasc Res. 1993;27:1538–1541
  17. Yoshimura N, Yamaguchi M, Oshima Y, Oka S, Ootaki Y, Hasegawa T, et al. Suppression of the secretion of atrial and brain natriuretic peptide after total cavopulmonary connection. J Thorac Cardiovasc Surg. 2000;120:764–769
  18. Costello JM, Backer CL, Checchia PA, Mavroudis C, Seipelt RG, Goodman DM. Effect of cardiopulmonary bypass and surgical intervention on the natriuretic hormone system in children. J Thorac Cardiovasc Surg. 2005;130:822–829
  19. Zhang Y, Carreras D, de Bold AJ. Discoordinate re-expression of cardiac fetal genes in N(omega)-nitro-L-arginine methyl ester (L-NAME) hypertension. Cardiovasc Res. 2003;57:158–167
  20. Schaub MC, Hefti MA, Harder BA, Eppenberger HM. Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes. J Mol Med. 1997;75:901–920
  21. Hama N, Itoh H, Shirakami G, Nakagawa O, Suga S, Ogawa Y, et al. Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction. Circulation. 1995;92:1558–1564
  22. Ma KK, Ogawa T, de Bold AJ. Selective upregulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro-inflammatory cytokines and by conditioned medium derived from mixed lymphocyte reactions via p38 MAP kinase. J Mol Cell Cardiol. 2004;36:505–513
  23. Hopkins WE, Chen Z, Fukagawa NK, Hall C, Knot HJ, LeWinter MM. Increased atrial and brain natriuretic peptides in adults with cyanotic congenital heart disease: enhanced understanding of the relationship between hypoxia and natriuretic peptide secretion. Circulation. 2004;109:2872–2877
  24. Suda K, Matsumura M, Matsumoto M. Clinical implication of plasma natriuretic peptides in children with ventricular septal defect. Pediatr Int. 2003;45:249–254
  25. Law YM, Ettedgui J, Beerman L, Maisel A, Tofovic S. Comparison of plasma B-type natriuretic peptide levels in single ventricle patients with systemic ventricle heart failure versus isolated cavopulmonary failure. Am J Cardiol. 2006;98:520–524
  26. Koch A, Zink S, Singer H. B-type natriuretic peptide in paediatric patients with congenital heart disease. Eur Heart J. 2006;27:861–866
  27. Hjortdal VE, Stenbog EV, Ravn HB, Emmertsen K, Jensen KT, Pedersen EB, et al. Neurohormonal activation late after cavopulmonary connection. Heart. 2000;83:439–443
  28. Wahlander H, Westerlind A, Lindstedt G, Lundberg PA, Holmgren D. Increased levels of brain and atrial natriuretic peptides after the first palliative operation, but not after a bidirectional glenn anastomosis, in children with functionally univentricular hearts. Cardiol Young. 2003;13:268–274
  29. Cowley CG, Bradley JD, Shaddy RE. B-type natriuretic peptide levels in congenital heart disease. Pediatr Cardiol. 2004;25:336–340

 This research was supported in part by grants K08 HL086513 (P.E.O.), K23 HL079922 (R.L.K.), HL61284 (J.R.F.), and UL RR024131-01 from the National Center for Research Resources, all from the National Institutes of Health, and from the Foundation Leducq (J.R.F.) and Biosite Diagnostic (J.R.F.). J.H.H. was supported in part by the Department of Pediatrics, Kaohsiung Medical University Hospital, Taiwan.

PII: S0022-5223(07)01870-3

doi: 10.1016/j.jtcvs.2007.10.040

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 746-753 , April 2008