The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 2 , Pages 283-291.e1 , February 2008

Transmyocardial revascularization to enhance myocardial vasculogenesis and hemodynamic function

Received 24 May 2007 ,Revised 11 September 2007 ,Accepted 24 September 2007.

References 

  1. Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K, et al. Heart disease and stroke statistics—2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007;115:e69–e171
  2. Kohmoto T, Argenziano M, Yamamoto N, Vliet KA, Gu A, DeRosa CM, et al. Assessment of transmyocardial perfusion in alligator hearts. Circulation. 1997;95:1585–1591
  3. Allen KB, Dowling RD, Schuch DR, Pfeffer TA, Marra S, Lefrak EA, et al. Adjunctive transmyocardial revascularization: five-year follow-up of a prospective, randomized trial. Ann Thorac Surg. 2004;78:458–465
  4. Allen KB, Dowling RD, Fudge TL, Schoettle GP, Selinger SL, Gangahar DM, et al. Comparison of transmyocardial revascularization with medical therapy in patients with refractory angina. N Engl J Med. 1999;341:1029–1036
  5. Frazier OH, March RJ, Horvath KA. Transmyocardial revascularization with a carbon dioxide laser in patients with end-stage coronary artery disease. N Engl J Med. 1999;341:1021–1028
  6. Burkhoff D, Schmidt S, Schulman SP, Myers J, Resar J, Becker LC, et al. Transmyocardial laser revascularisation compared with continued medical therapy for treatment of refractory angina pectoris: a prospective randomised trial. ATLANTIC Investigators. Angina Treatments–Lasers and Normal Therapies in Comparison. Lancet. 1999;354:885–890
  7. Horvath KA, Aranki SF, Cohn LH, March RJ, Frazier OH, Kadipasaoglu KA, et al. Sustained angina relief 5 years after transmyocardial laser revascularization with a CO2 laser. Circulation. 2001;104(12 Suppl 1):I81–I84
  8. Bridges CR, Horvath KA, Nugent WC, Shahian DM, Haan CK, Shemin RJ, et al. The Society of Thoracic Surgeons practice guideline series: transmyocardial laser revascularization. Ann Thorac Surg. 2004;77:1494–1502
  9. Kohmoto T, Fisher PE, Gu A, Zhu SM, Yano OJ, Spotnitz HM, et al. Does blood flow through holmium:YAG transmyocardial laser channels?. Ann Thorac Surg. 1996;61:861–868
  10. Wadia Y, Khaki A, Kajitani M, Mori Y, Irvine T, Sahn D, et al. Effects of transmyocardial laser revascularization by using a prototype pulsed CO2 laser on contractility and perfusion of chronically ischemic myocardium in a porcine model. ASAIO J. 2000;46:786–791
  11. Kohmoto T, Fisher PE, Gu A, Zhu SM, DeRosa CM, Smith CR, et al. Physiology, histology, and 2-week morphology of acute transmyocardial channels made with a CO2 laser. Ann Thorac Surg. 1997;63:1275–1283
  12. O'Konski MS, White FC, Longhurst J, Roth D, Bloor CM. Ameroid constriction of the proximal left circumflex coronary artery in swine. A model of limited coronary collateral circulation. Am J Cardiovasc Pathol. 1987;1:69–77
  13. Hamawy AH, Lee LY, Samy SA, Polce DR, Szulc M, Vazquez M, et al. Transmyocardial laser revascularization dose response: enhanced perfusion in a porcine ischemia model as a function of channel density. Ann Thorac Surg. 2001;72:817–822
  14. Roth DM, Maruoka Y, Rogers J, White FC, Longhurst JC, Bloor CM. Development of coronary collateral circulation in left circumflex ameroid-occluded swine myocardium. Am J Physiol. 1987;253(5 Pt 2):H1279–H1288
  15. Hughes GC, Biswas SS, Yin B, Baklanov DV, Annex BH, Coleman RE, et al. A comparison of mechanical and laser transmyocardial revascularization for induction of angiogenesis and arteriogenesis in chronically ischemic myocardium. J Am Coll Cardiol. 2002;39:1220–1228
  16. Hughes GC, Kypson AP, Annex BH, Yin B, St Louis JD, Biswas SS, et al. Induction of angiogenesis after TMR: a comparison of holmium:YAG, CO2, and excimer lasers. Ann Thorac Surg. 2000;70:504–509
  17. Allen KB, Dowling RD, DelRossi AJ, Realyvasques F, Lefrak EA, Pfeffer TA, et al. Transmyocardial laser revascularization combined with coronary artery bypass grafting: a multicenter, blinded, prospective, randomized, controlled trial. J Thorac Cardiovasc Surg. 2000;119:540–549
  18. Szmitko PE, Fedak PW, Weisel RD, Stewart DJ, Kutryk MJ, Verma S. Endothelial progenitor cells: new hope for a broken heart. Circulation. 2003;107:3093–3100
  19. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000;95:952–958
  20. Hristov M, Erl W, Weber PC. Endothelial progenitor cells: mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol. 2003;23:1185–1189
  21. Rothe G, Barlage S, Schmitz G, Kloushe M. Flow cytometric assessment of haematopoietic stem and progenitor cells. J Lab Med. 2003;27:175–181
  22. Tong Q, Zheng L, Lin L, Li B, Wang D, Huang C, et al. Participation of the PI-3K/Akt-NF-kappa B signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells. Respir Res. 2006;7:101
  23. Sasaki H, Ray PS, Zhu L, Galang N, Maulik N. Oxidative stress due to hypoxia/reoxygenation induces angiogenic factor VEGF in adult rat myocardium: possible role of NFkappaB. Toxicology. 2000;155:27–35
  24. Sasaki H, Ray PS, Zhu L, Otani H, Asahara T, Maulik N. Hypoxia/reoxygenation promotes myocardial angiogenesis via an NF kappa B–dependent mechanism in a rat model of chronic myocardial infarction. J Mol Cell Cardiol. 2001;33:283–294
  25. Karin M. Nuclear factor-kappaB in cancer development and progression. Nature. 2006;441:431–436
  26. Takahashi K, Ito Y, Morikawa M, Kobune M, Huang J, Tsukamoto M, et al. Adenoviral-delivered angiopoietin-1 reduces the infarction and attenuates the progression of cardiac dysfunction in the rat model of acute myocardial infarction. Mol Ther. 2003;8:584–592
  27. Siddiqui AJ, Blomberg P, Wardell E, Hellgren I, Eskandarpour M, Islam KB, et al. Combination of angiopoietin-1 and vascular endothelial growth factor gene therapy enhances arteriogenesis in the ischemic myocardium. Biochem Biophys Res Comm. 2003;310:1002–1009
  28. Gee MS, Procopio WN, Makonnen S, Feldman MD, Yeilding NM, Lee WM. Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy. Am J Pathol. 2003;162:183–193
  29. Atluri P, Liao GP, Panlilio CM, Hsu VM, Leskowitz MJ, Morine KJ, et al. Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy. Ann Thorac Surg. 2006;81:1728–1736
  30. Woo YJ, Panlilio CM, Cheng RK, Liao GP, Atluri P, Hsu VM, et al. Therapeutic delivery of cyclin A2 induces myocardial regeneration and enhances cardiac function in ischemic heart failure. Circulation. 2006;114(1 Suppl):I206–I213
  31. Muhling OM, Wang Y, Jerosch-Herold M, Cayton MM, Wann LS, Mirhoseini MM, et al. Improved myocardial function after transmyocardial laser revascularization according to cine magnetic resonance in a porcine model. J Thorac Cardiovasc Surg. 2004;128:391–395
  32. Rafii S, Meeus S, Dias S, Hattori K, Heissig B, Shmelkov S, et al. Contribution of marrow-derived progenitors to vascular and cardiac regeneration. Semin Cell Dev Biol. 2002;13:61–67
  33. Assmus B, Schachinger V, Teupe C, Britten M, Lehmann R, Dobert N, et al. Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI). Circulation. 2002;106:3009–3017
  34. Britten MB, Abolmaali ND, Assmus B, Lehmann R, Honold J, Schmitt J, et al. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation. 2003;108:2212–2218
  35. Yeh ET, Zhang S, Wu HD, Korbling M, Willerson JT, Estrov Z. Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation. 2003;108:2070–2073
  36. Asai T, Yamamoto S, Ishino K, Kohmoto T, Kuriyama M, Kato G, et al. Time-dependent regional myocardial denervation as a nonspecific response to transmyocardial laser revascularization. Ann Thorac Surg. 2005;80:1362–1369
  37. Yamamoto N, Gu A, DeRosa CM, Shimizu J, Zwas DR, Smith CR, et al. Radio frequency transmyocardial revascularization enhances angiogenesis and causes myocardial denervation in canine model. Lasers Surg Med. 2000;27:18–28
  38. Hughes GC, Baklanov DV, Biswas SS, Pippen AM, DeGrado TR, Coleman RE, et al. Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization. J Card Surg. 2004;19:21–27
  39. Minisi AJ, Topaz O, Quinn MS, Mohanty LB. Cardiac nociceptive reflexes after transmyocardial laser revascularization: implications for the neural hypothesis of angina relief. J Thorac Cardiovasc Surg. 2001;122:712–719
  40. Mouli SK, Fronza J, Greene R, Robert ES, Horvath KA. What is the optimal channel density for transmyocardial laser revascularization?. Ann Thorac Surg. 2004;78:1326–1331
  41. Allen GS. Mid-term results after thoracoscopic transmyocardial laser revascularization. Ann Thorac Surg. 2005;80:553–558

 Supported in part by grants from the National Institutes of Health National Heart Lung and Blood Institute/Thoracic Surgery Foundation for Research and Education (HL072812, YJW), unrestricted investigational grant from Cardiogenesis Corporation (YJW), and National Institutes of Health, National Heart Lung Blood Institute—Ruth L. Kirschstein National Research Service Award (Individual Fellowship 1 F32 HL79769-01, PA).

PII: S0022-5223(07)01659-5

doi: 10.1016/j.jtcvs.2007.09.043

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 2 , Pages 283-291.e1 , February 2008

Article Tools

* Image Usage & Resolution