The Journal of Thoracic and Cardiovascular Surgery
Volume 136, Issue 1 , Pages 46-51 , July 2008

Stress cardiac single-photon emission computed tomographic imaging late after coronary artery bypass surgery for risk stratification and estimation of time to cardiac events

  • Wanda Acampa, MD, PhD

      Affiliations

    • Institute of Biostructures and Bioimages, National Council of Research, Naples, Italy
    • Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
    • ,
  • Mario Petretta, MD

      Affiliations

    • Department of Internal Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    • ,
  • Laura Evangelista, MD

      Affiliations

    • SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
    • ,
  • Gianantonio Nappi, MD

      Affiliations

    • Department of Cardiothoracic Surgery, Second University, Naples, Italy
    • ,
  • Luca Luongo, MD

      Affiliations

    • Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
    • ,
  • Maria Piera Petretta, MD

      Affiliations

    • Department of Internal Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
    • ,
  • Alberto Cuocolo, MD

      Affiliations

    • Institute of Biostructures and Bioimages, National Council of Research, Naples, Italy
    • Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
    • SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
    • Corresponding Author InformationAddress for reprints: Alberto Cuocolo, MD, Department of Biomorphological and Functional Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy.

Received 18 July 2007 ,Revised 10 September 2007 ,Accepted 4 October 2007.

References 

  1. Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. Circulation. 1998;97:535–543
  2. Zellweger MJ, Lewin HC, Lai S, Dubois EA, Friedman JD, Germano G, et al. When to stress patients after coronary artery bypass surgery? Risk stratification in patients early and late post-CABG using stress myocardial perfusion SPECT: implications of appropriate clinical strategies. J Am Coll Cardiol. 2001;37:144–152
  3. Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, et al. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: a basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1995;26:639–647
  4. Gibbons RJ, Balady GJ, Bricker JT, Chaitman BR, Fletcher GF, Froelicher VF, et al. American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Committee to Update the 1997 Exercise Testing Guidelines. ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines). J Am Coll Cardiol. 2002;40:1531–1540
  5. Rizzello V, Poldermans D, Schinkel AF, Biagini E, Boersma E, Elhendy A, et al. Outcome after redo coronary artery bypass grafting in patients with ischaemic cardiomyopathy and viable myocardium. Heart. 2007;93:221–225
  6. Hachamovitch R, Hayes S, Friedman JD, Cohen I, Shaw LJ, Germano G, et al. Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans: what is the warranty period of a normal scan?. J Am Coll Cardiol. 2003;41:1329–1340
  7. Acampa W, Petretta M, Florimonte L, Mattera A, Cuocolo A. Prognostic value of exercise cardiac tomography performed late after percutaneous coronary intervention in symptomatic and symptom-free patients. Am J Cardiol. 2003;91:259–263
  8. Sharir T, Germano G, Kang X, Lewin HC, Miranda R, Cohen I, et al. Prediction of myocardial infarction versus cardiac death by gated myocardial perfusion SPECT: risk stratification by the amount of stress-induced ischemia and the poststress ejection fraction. J Nucl Med. 2001;42:831–837
  9. Cox DR. Regression models and life table. J R Stat Soc B. 1972;34:187–220
  10. Harrell FE, Lee KL, Califf RM, Pryor DB, Rosati RA. Regression modelling strategies for improved prognostic prediction. Stat Med. 1984;3:143–152
  11. Lawless J. Statistical models and methods for lifetime data. New York: John Wiley; 1982;
  12. Harrell FE. Predicting outcomes: applied survival analysis and logistic regression. Charlottesville (VA): University of Virginia; 2000;
  13. Shaw LJ, Iskandrian AE. Prognostic value of gated myocardial perfusion SPECT. J Nucl Cardiol. 2004;11:171–185
  14. Abramov D, Tamariz MG, Fremes SE, Guru V, Borger MA, Christakis GT, et al. Trends in coronary artery bypass surgery results: a recent, 9-year study. Ann Thorac Surg. 2000;70:84–90
  15. Shapira I, Isakov A, Heller I, Topilsky M, Pines A. Long-term follow-up after coronary artery bypass grafting reoperation. Chest. 1999;115:1593–1597
  16. Di Mauro M, Iacò AL, Contini M, Teodori G, Vitolla G, Pano M, et al. Reoperative coronary artery bypass grafting: analysis of early and late outcomes. Ann Thorac Surg. 2005;79:81–87
  17. He GW, Acuff TE, Ryan WH, He YH, Mack MJ. Determinants of operative mortality in reoperative coronary artery bypass rafting. J Thorac Cardiovasc Surg. 1995;110:971–978
  18. Lauer MS, Lytle B, Pashkow F, Snader CE, Marwick TH. Prediction of death and myocardial infarction by screening with exercise-thallium testing after coronary-artery-bypass grafting. Lancet. 1998;351:615–622
  19. Braunwald E, Mark DB, Jones RH. Unstable angina: diagnosis and management. AHCPR publication 94-0602. US Department of Health and Human Services. 1994;
  20. Berry C, Tardif JC, Bourassa MG. Coronary heart disease in patients with diabetes. Part I: recent advances in prevention and noninvasive management. J Am Coll Cardiol. 2007;49:631–642
  21. Berry C, Tardif JC, Bourassa MG. Coronary heart disease in patients with diabetes. Part II: recent advances in coronary revascularization. J Am Coll Cardiol. 2007;49:643–656
  22. Ledru F, Ducimetière P, Battaglia S, Courbon D, Beverelli F, Guize L, et al. New diagnostic criteria for diabetes and coronary artery disease: insights from an angiographic study. J Am Coll Cardiol. 2001;37:1543–1550
  23. Stadius ML, Alderman EL. Coronary artery revascularization. Critical need for, and consequences of, objective angiographic assessment of lesion severity. Circulation. 1990;82:2231–2234

 Stress cardiac tomography performed 5 years after CABG is useful to characterize the risk of cardiac events and its temporal variation. A parametric survival model estimates the predicted time to risk and the level of risk at specific time intervals after CABG.

PII: S0022-5223(07)01653-4

doi: 10.1016/j.jtcvs.2007.10.011

The Journal of Thoracic and Cardiovascular Surgery
Volume 136, Issue 1 , Pages 46-51 , July 2008

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