The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 792-798, April 2008

Acute β-blockade prevents myocardial β-adrenergic receptor desensitization and preserves early ventricular function after brain death

  • Prakash K. Pandalai, MD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Kelly M. McLean, MD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Department of Pediatric Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Christian F. Bulcao, MD, MBA

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Jodie Y. Duffy, PhD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Department of Pediatric Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Karen M. D'Souza, PhD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Walter H. Merrill, MD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Jeffrey M. Pearl, MD

      Affiliations

    • Department of Pediatric Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Shahab A. Akhter, MD

      Affiliations

    • Department of Surgery, Section of Cardiothoracic Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Corresponding Author InformationAddress for reprints: Shahab A. Akhter, Assistant Professor of Surgery, Section of Cardiac & Thoracic Surgery, The University of Chicago, 5841 S. Maryland Avenue, MC 5040, Chicago, IL 60637.

Received 31 May 2007; accepted 6 September 2007.

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 Supported by the National Institutes of Health (HL081472 to SAA, T32 HL007382-29 to PKP, and P021-040-N366 to KMM) and a research award from the American Surgical Association Foundation (to SAA).

PII: S0022-5223(07)01644-3

doi:10.1016/j.jtcvs.2007.09.038

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 792-798, April 2008

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