The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 777-783, April 2008

Reduction in postsurgical adhesion formation after cardiac surgery in a rabbit model using N,O-carboxymethyl chitosan to block cell adherence

  • Juan Zhou, MD, PhD

      Affiliations

    • Department of Surgery, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia
  • ,
  • Robert S. Liwski, MD, PhD

      Affiliations

    • Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia
  • ,
  • Clive Elson, PhD

      Affiliations

    • Department of Chemistry, Saint Mary's University, Halifax, Nova Scotia
  • ,
  • Timothy D.G. Lee, PhD

      Affiliations

    • Department of Surgery, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia
    • Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia
    • Corresponding Author InformationAddress for reprints: Tim Lee, PhD, Sir Charles Tupper Building, 5850 College Street, Dalhousie University, Halifax, NS, Canada, B3H 4H7.

Received 18 January 2007; received in revised form 23 August 2007; accepted 19 September 2007.

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 This work was supported in full by Kytogenics Pharmaceuticals Ltd. Dr Elson reports consulting fees, equity ownership, and employment by Kytogenics Pharma Ltd, the manufacturer of the gel described in this report. Drs Zhou, Liwski, and Lee have no financial interest in Kytogenics Ltd.

PII: S0022-5223(07)01638-8

doi:10.1016/j.jtcvs.2007.09.033

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 4 , Pages 777-783, April 2008