The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 1 , Pages 25-31 , January 2008

Less-invasive and highly effective method for preventing methicillin-resistant Staphylococcus aureus graft infection by local sustained release of vancomycin

  • Hisashi Sakaguchi, MD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Akira Marui, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Keiichi Hirose, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Takamasa Nomura, PhD

      Affiliations

    • Department of Microbiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Yoshio Arai, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Shyamal Chandra Bir, MD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Yuhong Huang, MD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Jiro Esaki, MD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Yasuhiko Tabata, PhD, DMSc, Dpharm

      Affiliations

    • The Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.
    • ,
  • Tadashi Ikeda, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Masashi Komeda, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • Corresponding Author InformationAddress for reprints: Masashi Komeda, MD, PhD, Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawara-cho, Sakyo-ku, Kyoto, 606-8507 Japan.

Received 28 February 2007 ,Revised 12 May 2007 ,Accepted 20 June 2007.

References 

  1. Huh J, Chen JC, Furman GM, Malki C, King B, Kafie F, et al. Local treatment of prosthetic vascular graft infection with multivesicular liposome-encapsulated amikacin. J Surg Res. 1998;74:54–58
  2. Jones L, Braithwaite BD, Davies B, Heather BP, Earnshaw JJ. Mechanism of late prosthetic vascular graft infection. Cardiovasc Surg. 1997;5:486–489
  3. Hernandez-Richter T, Schardey HM, Wittmann F, Mayr S, Schmitt-Sody M, Blasenbreu S, et al. Rifampin and triclosan but not silver is effective in preventing bacterial infection of vascular Dacron graft material. Eur J Endovasc Surg. 2003;26:550–557
  4. Henke PK, Bergamini TM, Rose SM, Richardson JD. Current options in prosthetic vascular graft infection. Am Surg. 1998;64:39–46
  5. Murphy GJ, Pararajasingam R, Nasim A, Dennis MJ, Sayers RD. Methicillin-resistant Staphylococcus aureus infection in vascular surgical patients. Ann R Coll Surg Engl. 2001;83:158–163
  6. Nasim A, Thompson MM, Naylor AR, Bell PRF, London NJM. The impact of MRSA on vascular surgery. Eur J Endovasc Surg. 2001;22:211–214
  7. Chiesa R, Astore D, Frigerio S, Garriboil L, Piccolo G, Castellano R, et al. Vascular prosthetic graft infection: epidemiology, bacteriology, pathogenesis and treatment. Acta Chir Belg. 2002;102:238–247
  8. Hirose K, Marui A, Arai Y, Nomura T, Inoue S, Kaneda K, et al. Sustained-release vancomycin sheet may help to prevent prosthetic graft methicillin-resistant Staphylococcus aureus infection. J Vasc Surg. 2006;44:377–382
  9. Zhu Y, Chian KS, Chan-Park MB, Mhaisalkar PS, Ratner BD. Protein bonding on biodegradable poly(L-lactide-co-caprolactone) membrane for esophageal tissue engineering. Biomaterials. 2006;27:68–78
  10. Giavaresi G, Tschon M, Borsari V, Daly JH, Liggat JJ, Fini M, et al. New polymers for drug delivery systems in orthopaedics: in vivo biocompatibility evaluation. Biomed Pharmacother. 2004;58:411–417
  11. Fujimoto K, Yamamura K, Osada T, Hayashi T, Nabeshima T, Matsushita M, et al. Subcutaneous tissue distribution of vancomycin from a fibrin glue/Dacron graft carrier. J Biomed Mater Res. 1997;36:564–567
  12. Giacometti A, Cirioni O, Ghiselli R, Goffi L, Mocchegiani F, Riva A, et al. Efficacy of polycationic peptides in preventing vascular graft infection due to Staphylococcus epidermidis. J Antimicrobial Chemother. 2000;46:751–756
  13. Yasim A, Guel M, Ciralik H, Ergun Y. Gelatin-sealed Dacron graft is not more susceptible to MRSA infection than PTFE graft. Eur J Endovasc Surg. 2006;32:425–430
  14. Chilukuri MD, Shah JC. Local delivery of vancomycin for prophylaxis of prosthetic device related infections. Pharm Res. 2005;22:563–572
  15. Koshiko S, Sasajima T, Muraki S, Azuma N, Yamazaki K, Chiba K, et al. Limitations in the use of rifampicin-gelatin grafts against virulent organisms. J Vasc Surg. 2002;35:779–785
  16. Hayes PD, Nasim A, London NJ, Sayers RD, Barrie WW, Bell PR, et al. In situ replacement of infected aortic grafts with rifampicin-bonded prostheses: the Leicester experience (1992 to 1998). J Vasc Surg. 2000;31:837–838
  17. Ricotta JJ, Faggioli GL, Stella A, Curl GR, Peer R, Upson J, et al. Total excision and extra-anatomical bypass for aortic graft infection. Am J Surg. 1991;162:145–149
  18. Seeger JM, Pretus HA, Welborn MB, Ozaki KC, Flynn TC, Huber TS. Long-term outcome after treatment of aortic graft infection with staged extra-anatomic bypass grafting and aortic graft removal. J Vasc Surg. 2000;32:451–461
  19. Young RM, Cherry KJ, Davis P, Gloviczki P, Bower TC, Panneton JM, et al. The results of in situ prosthetic replacement for infected aortic grafts. Am J Surg. 1999;178:136–140
  20. Gomes MN, Spear SL. Pedicled muscle flaps in the management of infected aortofemoral grafts. Cardiovasc Surg. 1994;2:70–77
  21. Nakajima N, Masuda M, Ichinose M, Ando M. A new method for the treatment of graft infection in the thoracic aorta: in situ preservation. Ann Thorac Surg. 1999;67:1994–1996

PII: S0022-5223(07)01199-3

doi: 10.1016/j.jtcvs.2007.06.027

The Journal of Thoracic and Cardiovascular Surgery
Volume 135, Issue 1 , Pages 25-31 , January 2008

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