The Journal of Thoracic and Cardiovascular Surgery
Volume 134, Issue 1 , Pages 20-22.e1 , July 2007

In vivo tissue engineering an autologous semilunar biovalve: Can we get what we want?

  • Hans-Hinrich Sievers, MD

      Affiliations

    • Corresponding Author InformationAddress for reprints: Hans-Hinrich Sievers, MD, University of Schleswig-Holstein, Campus Luebeck, Department of Cardiac Surgery, Ratzeburger Allee 160, Luebeck D-23538 Germany.

Received 12 March 2007 ,Revised 21 March 2007 ,Accepted 29 March 2007.

References 

  1. Hove JR, Koster RW, Forouhar AS, Acevedo-Bolton G, Fraser SE, Gharib M. Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature. 2003;421:172–177
  2. Hagmann M. A gene that scrambles your heart. Science. 1999;283:1091–1093
  3. Rabkin-Aikawa E, Farber M, Aikawa M, Schoen FJ. Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. J Heart Valve Dis. 2004;13:841–847
  4. Yacoub MH, Kilner PJ, Birks EJ, Misfeld M. The aortic outflow and root: a tale of dynamism and crosstalk. Ann Thorac Surg. 1999;68(Suppl 1):37–43
  5. Doehring TC, Kahelin M, Vesely I. Mesostructures of the aortic valve. J Heart Valve Dis. 2005;14:679–686
  6. Sutherland FW, Perry TE, Yu Y, Sherwood MC, Rabkin E, Masuda Y, et al. From stem cells to viable autologous semilunar heart valve. Circulation. 2005;111:2783–2791
  7. Hayashida K, Kanda K, Yaku H, Ando J, Nakayama Y. Development of an in vivo tissue-engineered autologous heart valve (the Biovalve). J Thorac Cardiovasc Surg. 2007;134:152–159
  8. Hallin RW, Sweetman WR Sparks and his associates. The Sparks’ mandril graft (A seven year follow-up of mandril grafts placed by Charles H). Am J Surg. 1976;132:221–223

PII: S0022-5223(07)00625-3

doi: 10.1016/j.jtcvs.2007.03.028

The Journal of Thoracic and Cardiovascular Surgery
Volume 134, Issue 1 , Pages 20-22.e1 , July 2007

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