Warm nondepolarizing adenosine and lidocaine cardioplegia: Continuous versus intermittent delivery

CVR measured after 38-minute arrest (A) and 58-minute arrest (B) in hearts arrested for 40 or 60 minutes with continuous or intermittent delivery of AL or lidocaine cardioplegia. (*P ≤ .05 lidocaine group compared with AL intermittent group after 38-minute arrest; **P ≤ .01 lidocaine group compared with AL intermittent group after 58-minute arrest.) For the method of CVR calculation, see “Materials and Methods.” AL, Adenosine and lidocaine; CVR, coronary vascular resistance; Cont, continuous; Int, intermittent.

Percentage of pre-arrest values of (A) aortic flow and (B) coronary flow recorded during the 60-minute reperfusion period in hearts arrested with ♢: 40 minutes of continuous AL, □: 40 minutes of intermittent AL, x: 60 minutes of continuous AL, Δ: 60 minutes of intermittent AL, and ■: 60 minutes of intermittent lidocaine. *Significant difference in aortic flow between the 60-minute intermittent lidocaine group compared with 60-minute AL intermittent group (P ≤ .01) and 60-minute AL continuous group (P ≤ .05), and *significant difference in coronary flow between the 60-minute intermittent lidocaine group compared with 60-minute AL intermittent group (P ≤ .01).